Accumulation of aluminium in lamellar bone after implantation of titanium plates, Ti-6Al-4V screws, hydroxyapatite granules.

Titanium plates, Ti6Al4V screws and surrounding tissues, and biopsies of hydroxyapatite (Osprovit) grafts of maxillary sinus lifting were investigated to evaluate the release and accumulation of ions. Optical microscopy, SEM and X-ray microanalysis were carried out to evaluate the plates and screws removed from patients presenting inflammation and biopsies. Ions release from metallic appliances or leaching from granules towards soft tissues was observed. An accumulation of aluminium but not titanium was found in soft tissues. A peculiar accumulation of aluminium in the dense lamella of newly formed bone was recorded. The results seem to indicate that biological perturbations may be related to aluminium release from the tested biomaterials. The aluminium content of these biomaterials, its diffusion and accumulation are discussed. Further studies on ion release from biomaterials and aluminium fate in skeletal tissues are suggested. IDS Number: 808GS PMID: 15020159

Accumulation of aluminium in lamellar bone after implantation of titanium plates, Ti-6Al-4V screws, hydroxyapatite granules / Zaffe, Davide; Bertoldi, Carlo; Consolo, Ugo. - In: BIOMATERIALS. - ISSN 0142-9612. - STAMPA. - 25(2004), pp. 3837-3844.

Data di pubblicazione:	2004
Titolo:	Accumulation of aluminium in lamellar bone after implantation of titanium plates, Ti-6Al-4V screws, hydroxyapatite granules.
Autore/i:	Zaffe, Davide; Bertoldi, Carlo; Consolo, Ugo
Autore/i UNIMORE:	ZAFFE, Davide BERTOLDI, Carlo CONSOLO, Ugo
Digital Object Identifier (DOI):	http://dx.doi.org/10.1016/j.biomaterials.2003.10.020
Rivista:	BIOMATERIALS
Volume:	25
Pagina iniziale:	3837
Pagina finale:	3844
Codice identificativo ISI:	WOS:000220558200053
Codice identificativo Scopus:	2-s2.0-1542358204
Codice identificativo Pubmed:	15020159
Citazione:	Accumulation of aluminium in lamellar bone after implantation of titanium plates, Ti-6Al-4V screws, hydroxyapatite granules / Zaffe, Davide; Bertoldi, Carlo; Consolo, Ugo. - In: BIOMATERIALS. - ISSN 0142-9612. - STAMPA. - 25(2004), pp. 3837-3844.
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http://hdl.handle.net/11380/595544

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