A process of chemical depolymerization of dermatan sulfate (DS) byfree radicals ispresented. The low molecular weight dermatan sulfate (LMW-DS) obtained by radicai fragmentation is characterized by physico-chemicalproperties (molecular weight, sulfate/carboxyl ratto, uronic acid percentage, electrophoretic profile), purity (by thè agarose electrophoretic method) and structure (specific enzymatic cleavage and "C-NMR). Physico-chemical properties and structure of LMW-DS are compared with those of thè parent DS.

Analytical techniques for studying structures of dermatan sulfate and low molecular weight dermatan sulfate / Volpi, Nicola; Mascellani, G.; Bianchini, P.; Liverani, L.. - In: IL FARMACO. - ISSN 0014-827X. - STAMPA. - XLVII, 47(suppl. 5):(1992), pp. 841-853.

Analytical techniques for studying structures of dermatan sulfate and low molecular weight dermatan sulfate

VOLPI, Nicola;
1992

Abstract

A process of chemical depolymerization of dermatan sulfate (DS) byfree radicals ispresented. The low molecular weight dermatan sulfate (LMW-DS) obtained by radicai fragmentation is characterized by physico-chemicalproperties (molecular weight, sulfate/carboxyl ratto, uronic acid percentage, electrophoretic profile), purity (by thè agarose electrophoretic method) and structure (specific enzymatic cleavage and "C-NMR). Physico-chemical properties and structure of LMW-DS are compared with those of thè parent DS.
1992
XLVII, 47(suppl. 5)
841
853
Analytical techniques for studying structures of dermatan sulfate and low molecular weight dermatan sulfate / Volpi, Nicola; Mascellani, G.; Bianchini, P.; Liverani, L.. - In: IL FARMACO. - ISSN 0014-827X. - STAMPA. - XLVII, 47(suppl. 5):(1992), pp. 841-853.
Volpi, Nicola; Mascellani, G.; Bianchini, P.; Liverani, L.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/594806
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