Ophthalmic diagnosis through measurements of ocular tissues autofluorescence has recently reached its first clinical maturity. This technique is intrinsically non-invasive and, thanks to the availability of a new family of measuring instruments, is becoming reliable even if performed in a few seconds and is of no burden to the patient. Diagnostic methods based on ocular tissue autofluorescence could become important tools in the prevention of a number of diseases which may lead to blindness, and therefore have a great social impact. The present paper is intended to give, from one side, an update of the rationale concerning fluorophores in the eye and their absorption and fluorescence properties; from the other, it offers an overview of ophthalmic fluorescence techniques aimed at the detection, quantitation and discrimination of ocular autofluorescing substances, highlighting their usefulness as a diagnostic aid in the early detection and prevention of ocular diseases.
Autofluorescence of ocular tissues: an update of measurement techniques for research and diagnosis / Franco, Docchio; Rovati, Luigi. - STAMPA. - 2971:(1997), pp. 2-7. (Intervento presentato al convegno SPIE photonic west tenutosi a S. Jose nel 1997).
Autofluorescence of ocular tissues: an update of measurement techniques for research and diagnosis
ROVATI, Luigi
1997
Abstract
Ophthalmic diagnosis through measurements of ocular tissues autofluorescence has recently reached its first clinical maturity. This technique is intrinsically non-invasive and, thanks to the availability of a new family of measuring instruments, is becoming reliable even if performed in a few seconds and is of no burden to the patient. Diagnostic methods based on ocular tissue autofluorescence could become important tools in the prevention of a number of diseases which may lead to blindness, and therefore have a great social impact. The present paper is intended to give, from one side, an update of the rationale concerning fluorophores in the eye and their absorption and fluorescence properties; from the other, it offers an overview of ophthalmic fluorescence techniques aimed at the detection, quantitation and discrimination of ocular autofluorescing substances, highlighting their usefulness as a diagnostic aid in the early detection and prevention of ocular diseases.
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