Infection of Langerhans cells (LC) by HIV is relevant for several reason. LC of mucosal epithelia may be among the first cells to be infected following mucosal HIV-1 exposure. Secondly, LC may serve as a reservoir for continued infection of CD4+T cells, especially in lymph nodes where epidermal LC migrate following antigenic activation. In this study we have shown that LC can be efficiently infected in vitro with HIV and can transmit the infection to other susceptible target cells.

In vitro infection of epidermal Langerhans cells with human immunodeficiency virus type 1 / G., Zambruno; G., Girolomoni; M. C., Re; E., Ramazzotti; Marconi, Alessandra; G., Furlini; M., Vignoli; M., La Placa; Giannetti, Alberto. - STAMPA. - (2) 378:(1995), pp. 453-455.

In vitro infection of epidermal Langerhans cells with human immunodeficiency virus type 1

MARCONI, Alessandra;GIANNETTI, Alberto
1995

Abstract

Infection of Langerhans cells (LC) by HIV is relevant for several reason. LC of mucosal epithelia may be among the first cells to be infected following mucosal HIV-1 exposure. Secondly, LC may serve as a reservoir for continued infection of CD4+T cells, especially in lymph nodes where epidermal LC migrate following antigenic activation. In this study we have shown that LC can be efficiently infected in vitro with HIV and can transmit the infection to other susceptible target cells.
(2) 378
453
455
G., Zambruno; G., Girolomoni; M. C., Re; E., Ramazzotti; Marconi, Alessandra; G., Furlini; M., Vignoli; M., La Placa; Giannetti, Alberto
In vitro infection of epidermal Langerhans cells with human immunodeficiency virus type 1 / G., Zambruno; G., Girolomoni; M. C., Re; E., Ramazzotti; Marconi, Alessandra; G., Furlini; M., Vignoli; M., La Placa; Giannetti, Alberto. - STAMPA. - (2) 378:(1995), pp. 453-455.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/593874
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