Neuropeptides (NP) are protein compounds contained both in the central and peripheral nervous system. They can be antidromically released from sensory nerves and are implicated in the so-called neurogenic inflammation. They also exert a number of functions within the immune system and are thought to act as trophic as well as mitogenic substances. Several NP have been detected in human skin by immunohistochemical and radioimmunological techniques, and recent reports have demonstrated that NP could be involved in the mechanisms of certain dermatoses. The involvement of NP in either physiological or pathophysiological skin conditions is discussed. Moreover, a few questions, which still need to be addressed, are raised, and future directions this field of research should take are outlined.

Neuropeptides And Skin Inflammation / Pincelli, Carlo; F., Fantini; Giannetti, Alberto. - In: DERMATOLOGY. - ISSN 1018-8665. - STAMPA. - 187:(1993), pp. 153-158.

Neuropeptides And Skin Inflammation

PINCELLI, Carlo;GIANNETTI, Alberto
1993

Abstract

Neuropeptides (NP) are protein compounds contained both in the central and peripheral nervous system. They can be antidromically released from sensory nerves and are implicated in the so-called neurogenic inflammation. They also exert a number of functions within the immune system and are thought to act as trophic as well as mitogenic substances. Several NP have been detected in human skin by immunohistochemical and radioimmunological techniques, and recent reports have demonstrated that NP could be involved in the mechanisms of certain dermatoses. The involvement of NP in either physiological or pathophysiological skin conditions is discussed. Moreover, a few questions, which still need to be addressed, are raised, and future directions this field of research should take are outlined.
1993
187
153
158
Neuropeptides And Skin Inflammation / Pincelli, Carlo; F., Fantini; Giannetti, Alberto. - In: DERMATOLOGY. - ISSN 1018-8665. - STAMPA. - 187:(1993), pp. 153-158.
Pincelli, Carlo; F., Fantini; Giannetti, Alberto
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/592757
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