An HPTLC method is described for the simultaneous determination of glycyrrhizinic acid tripotassium salt (3K-G), 18 alpha- and 18 beta-glycyrrhetinic acid (18 alpha-GA, 18 beta-GA) in rat plasma, after oral administration of 3K-G (30 mg/kg once a day for 30 days). Systolic pressure and the volume of urine excreted in 24 hours were recorded during this period to observe any drug-induced effects.

Determination of glycyrrhizin and 18 alpha-, 18 beta-glycyrrhetinic acid in rat plasma by high-performance thin-layer chromatography / Vampa, Gabriella; Benvenuti, Stefania; Rossi, Tiziana. - In: IL FARMACO. - ISSN 0014-827X. - STAMPA. - 47(5 Suppl):(1992), pp. 825-832.

Determination of glycyrrhizin and 18 alpha-, 18 beta-glycyrrhetinic acid in rat plasma by high-performance thin-layer chromatography.

VAMPA, Gabriella;BENVENUTI, Stefania;ROSSI, Tiziana
1992

Abstract

An HPTLC method is described for the simultaneous determination of glycyrrhizinic acid tripotassium salt (3K-G), 18 alpha- and 18 beta-glycyrrhetinic acid (18 alpha-GA, 18 beta-GA) in rat plasma, after oral administration of 3K-G (30 mg/kg once a day for 30 days). Systolic pressure and the volume of urine excreted in 24 hours were recorded during this period to observe any drug-induced effects.
47(5 Suppl)
825
832
Determination of glycyrrhizin and 18 alpha-, 18 beta-glycyrrhetinic acid in rat plasma by high-performance thin-layer chromatography / Vampa, Gabriella; Benvenuti, Stefania; Rossi, Tiziana. - In: IL FARMACO. - ISSN 0014-827X. - STAMPA. - 47(5 Suppl):(1992), pp. 825-832.
Vampa, Gabriella; Benvenuti, Stefania; Rossi, Tiziana
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/592300
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