Objective: To investigate the morphology, scalp topography and temporal relationship with orbicularis oculi muscle contraction ofbilateral blink related spikes (BRS) in a 7-year-old boy with chromosomopathy, mild mental retardation and left spontaneous centrotemporal spikes (SS).Methods: The patient underwent video-polygraphic recordings with off-line analysis of SS and BRS by means of spike-averaging and orbicularis oculi contraction-locked averaging techniques respectively. EEG activity related to reflex blinking (evoked by glabellar tapping) was also studied.Results: SS and BRS presented the same morphology, characterised by four peaks (P1, N1, P2, N2). SS were located over the left centroparietal regions, while BRS were placed over both left and right centrotemporoparietal regions and constantly followed the contraction of orbicularis oculi with overlapping peak latencies over C3 and C4 electrodes (P1 72 ms; N1 115 ms; P2 164 ms; N2 236 ms). Refex blinking evoked a small waveform with the same features as BRS.Conclusions: Our fndings suggest that both involuntary and reflex blinking can act as a form of sensory stimulation probably engaging similar nervous pathways and cortical sources in generating EEG abnormalities: the trigeminal system.

Bilateral centrotemporal spikes triggered by blinking: an unusual form of sensory input with related cortical EEG activity / Vetrugno, R.; Meletti, Stefano; Plazzi, G.; Posar, A.; Santucci, M.; Rossi, P. G.; Lugaresi, E.; Liguori, R.. - In: CLINICAL NEUROPHYSIOLOGY. - ISSN 1388-2457. - STAMPA. - 110:(1999), pp. 1995-1999. [10.1016/S1388-2457(99)00156-X]

Bilateral centrotemporal spikes triggered by blinking: an unusual form of sensory input with related cortical EEG activity

MELETTI, Stefano;G. Plazzi;
1999

Abstract

Objective: To investigate the morphology, scalp topography and temporal relationship with orbicularis oculi muscle contraction ofbilateral blink related spikes (BRS) in a 7-year-old boy with chromosomopathy, mild mental retardation and left spontaneous centrotemporal spikes (SS).Methods: The patient underwent video-polygraphic recordings with off-line analysis of SS and BRS by means of spike-averaging and orbicularis oculi contraction-locked averaging techniques respectively. EEG activity related to reflex blinking (evoked by glabellar tapping) was also studied.Results: SS and BRS presented the same morphology, characterised by four peaks (P1, N1, P2, N2). SS were located over the left centroparietal regions, while BRS were placed over both left and right centrotemporoparietal regions and constantly followed the contraction of orbicularis oculi with overlapping peak latencies over C3 and C4 electrodes (P1 72 ms; N1 115 ms; P2 164 ms; N2 236 ms). Refex blinking evoked a small waveform with the same features as BRS.Conclusions: Our fndings suggest that both involuntary and reflex blinking can act as a form of sensory stimulation probably engaging similar nervous pathways and cortical sources in generating EEG abnormalities: the trigeminal system.
1999
110
1995
1999
Bilateral centrotemporal spikes triggered by blinking: an unusual form of sensory input with related cortical EEG activity / Vetrugno, R.; Meletti, Stefano; Plazzi, G.; Posar, A.; Santucci, M.; Rossi, P. G.; Lugaresi, E.; Liguori, R.. - In: CLINICAL NEUROPHYSIOLOGY. - ISSN 1388-2457. - STAMPA. - 110:(1999), pp. 1995-1999. [10.1016/S1388-2457(99)00156-X]
Vetrugno, R.; Meletti, Stefano; Plazzi, G.; Posar, A.; Santucci, M.; Rossi, P. G.; Lugaresi, E.; Liguori, R.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/590770
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