The reaction of N-substituted 4-methyl-2-pyrrolidinones, carrying not less than two chlorine atoms on the C(3) and C(6) carbons afforded with alkaline methoxide in methanol, under mild conditions, the corresponding 5-methoxy or 5,5-dimethoxy-4-methyl-3-pyrrolin-2-ones in satisfactory yields.

Unusual access to 5-methoxy or 5,5-dimethoxy-4-methyl-3-pyrrolin-2-ones from chlorinated 4-methyl-pyrrolidin-2-ones / Bellesia, Franco; L., DE BUYCK; M. V., Colucci; Ghelfi, Franco; I., Laureyn; Libertini, Emanuela; Mucci, Adele; Pagnoni, Ugo Maria; Pinetti, Adriano; T. M., Rogge; C. V., Stevens. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 42:27(2001), pp. 4573-4575. [10.1016/S0040-4039(01)00792-4]

Unusual access to 5-methoxy or 5,5-dimethoxy-4-methyl-3-pyrrolin-2-ones from chlorinated 4-methyl-pyrrolidin-2-ones

BELLESIA, Franco;GHELFI, Franco;LIBERTINI, Emanuela;MUCCI, Adele;PAGNONI, Ugo Maria;PINETTI, Adriano;
2001

Abstract

The reaction of N-substituted 4-methyl-2-pyrrolidinones, carrying not less than two chlorine atoms on the C(3) and C(6) carbons afforded with alkaline methoxide in methanol, under mild conditions, the corresponding 5-methoxy or 5,5-dimethoxy-4-methyl-3-pyrrolin-2-ones in satisfactory yields.
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Unusual access to 5-methoxy or 5,5-dimethoxy-4-methyl-3-pyrrolin-2-ones from chlorinated 4-methyl-pyrrolidin-2-ones / Bellesia, Franco; L., DE BUYCK; M. V., Colucci; Ghelfi, Franco; I., Laureyn; Libertini, Emanuela; Mucci, Adele; Pagnoni, Ugo Maria; Pinetti, Adriano; T. M., Rogge; C. V., Stevens. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 42:27(2001), pp. 4573-4575. [10.1016/S0040-4039(01)00792-4]
Bellesia, Franco; L., DE BUYCK; M. V., Colucci; Ghelfi, Franco; I., Laureyn; Libertini, Emanuela; Mucci, Adele; Pagnoni, Ugo Maria; Pinetti, Adriano; T. M., Rogge; C. V., Stevens
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/584664
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