Glucose sensing using the Brewster reflection: polarimetric ray-tracing based upon an anatomical eye model

In this paper we present theoretical analysis to support the polarimetric approach for glucose detection in the human eye applying Brewster reflection off the ocular lens. The theoretical eye model of Navarro, which is based upon anatomical data, was used to perform ray-tracing, whereas the electromagnetic and polarization parameters of light propagation through the eye-media were calculated. The errors in glucose concentration determination due to refraction and deviation from the ideal optical path were calculated under different conditions. Effects of using incident linearly and circularly polarized light and variation of intersection condition of the incoming light beam with the anterior corneal surface were taken into consideration. Calculations were performed for a wide spectral range by applying dispersion curves for the eye-media. These simulations show the potential and the limits of the proposed optical approach.