Functional magnetic resonance imaging (fMRI) plays a dominant role in human brain mapping studies. As of today, no standards exist for processing fMRI data and analysis techniques are often associated to the different stimulation paradigms used to acquire functional data. Being able to estimate the hemodynamic response following a single execution of a task permits to characterize its relationship to different aspects of the stimulus, and of the subject’s performance. This works is aimed to test a strategy for the characterization of single trial-related BOLD fMRI responses based on the self-organizing maps method of Kohonen (SOMs). Analysis have been carried out on synthetic fMRI images modeling activation and on data from a single-event fMRI experiment on one human subject performing a basic motor task. Results were able to define the potentiality range for this data-driven methodology in monitoring the evolution of the BOLD response deriving from a single stimulation.

Single-Trial Characterization of BOLD fMRI Responses by Self-Organizing Neural Networks / Manginelli, Angela; Duzzi, Davide; Lui, Fausta; Maieron, Marta; Baraldi, Patrizia. - In: IFMBE PROCEEDINGS (CD). - ISSN 1727-1983. - ELETTRONICO. - 6:(2004), pp. nd-nd. ((Intervento presentato al convegno X Mediterranean Conference on Medical and Biological Engineering "Health in the Information Society tenutosi a Ischia nel 31 July - 5 August 2004.

Single-Trial Characterization of BOLD fMRI Responses by Self-Organizing Neural Networks

MANGINELLI, ANGELA;DUZZI, Davide;LUI, Fausta;MAIERON, MARTA;BARALDI, Patrizia
2004

Abstract

Functional magnetic resonance imaging (fMRI) plays a dominant role in human brain mapping studies. As of today, no standards exist for processing fMRI data and analysis techniques are often associated to the different stimulation paradigms used to acquire functional data. Being able to estimate the hemodynamic response following a single execution of a task permits to characterize its relationship to different aspects of the stimulus, and of the subject’s performance. This works is aimed to test a strategy for the characterization of single trial-related BOLD fMRI responses based on the self-organizing maps method of Kohonen (SOMs). Analysis have been carried out on synthetic fMRI images modeling activation and on data from a single-event fMRI experiment on one human subject performing a basic motor task. Results were able to define the potentiality range for this data-driven methodology in monitoring the evolution of the BOLD response deriving from a single stimulation.
X Mediterranean Conference on Medical and Biological Engineering "Health in the Information Society
Ischia
31 July - 5 August 2004
6
nd
nd
Manginelli, Angela; Duzzi, Davide; Lui, Fausta; Maieron, Marta; Baraldi, Patrizia
Single-Trial Characterization of BOLD fMRI Responses by Self-Organizing Neural Networks / Manginelli, Angela; Duzzi, Davide; Lui, Fausta; Maieron, Marta; Baraldi, Patrizia. - In: IFMBE PROCEEDINGS (CD). - ISSN 1727-1983. - ELETTRONICO. - 6:(2004), pp. nd-nd. ((Intervento presentato al convegno X Mediterranean Conference on Medical and Biological Engineering "Health in the Information Society tenutosi a Ischia nel 31 July - 5 August 2004.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/464150
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