Aging, considered as a chronological and/or biological event, is an extremely complex and multifactorial process, which may represent the consequences of environmental noxae interfering with genetic and developmental programs.The extracellular matrix plays a crucial role in age-related degenerations, and the so-called "premature aging syndromes" give further evidence for the complexity of the relationships between connective tissue, age and diseases. Several reports already focused on the correlations between age and phenotypic expression of mesenchimal cells in vitro; moreover, it was also pointed out that morphological and functional alterations of connective tissues, at some extent, might be related in vivo to increasing age. Correlation between morphologic data and proteomic analyses sustains the hypothesis that senescence is the result of both genetic and epigenetic factors.

Ageing of connective tissues / Quaglino, Daniela; Gheduzzi, Dealba; Boraldi, Federica; Ronchetti, Ivonne. - In: HISTOLOGY AND HISTOPATHOLOGY. - ISSN 0213-3911. - STAMPA. - S1:(2005), pp. 61-62. ((Intervento presentato al convegno First international congress of histology and tissue engineering tenutosi a Alcalà de Henares Madrid nel 14-17 Settembre 2005.

Ageing of connective tissues

QUAGLINO, Daniela;GHEDUZZI, Dealba;BORALDI, Federica;RONCHETTI, Ivonne
2005

Abstract

Aging, considered as a chronological and/or biological event, is an extremely complex and multifactorial process, which may represent the consequences of environmental noxae interfering with genetic and developmental programs.The extracellular matrix plays a crucial role in age-related degenerations, and the so-called "premature aging syndromes" give further evidence for the complexity of the relationships between connective tissue, age and diseases. Several reports already focused on the correlations between age and phenotypic expression of mesenchimal cells in vitro; moreover, it was also pointed out that morphological and functional alterations of connective tissues, at some extent, might be related in vivo to increasing age. Correlation between morphologic data and proteomic analyses sustains the hypothesis that senescence is the result of both genetic and epigenetic factors.
First international congress of histology and tissue engineering
Alcalà de Henares Madrid
14-17 Settembre 2005
S1
61
62
Quaglino, Daniela; Gheduzzi, Dealba; Boraldi, Federica; Ronchetti, Ivonne
Ageing of connective tissues / Quaglino, Daniela; Gheduzzi, Dealba; Boraldi, Federica; Ronchetti, Ivonne. - In: HISTOLOGY AND HISTOPATHOLOGY. - ISSN 0213-3911. - STAMPA. - S1:(2005), pp. 61-62. ((Intervento presentato al convegno First international congress of histology and tissue engineering tenutosi a Alcalà de Henares Madrid nel 14-17 Settembre 2005.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/457464
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