Baker's yeast reduces 1,1,1-trifluoro-2,4-pentanedione with high regio- and enantio-selectivity to give (S)-5,5,5-trifluoro-4-hydroxy-2-pentanone. The enantiomeric excess was determined by Mosher's method and the absolute configuration was established by correlation with ethyl (R)-(+)-4,4,4-trifluoro-3-hydroxybutanoate.

Enantioselective Synthesis of (S)-(Ð)-5,5,5-Trifluoro-4-Hydroxy-2-Pentanone by Baker's Yeast Reduction / Bucciarelli, Maria; Forni, Arrigo; Moretti, Irene; Prati, Fabio; Torre, Giovanni. - In: GAZZETTA CHIMICA ITALIANA. - ISSN 0016-5603. - STAMPA. - 120:(1990), pp. 99-99.

Enantioselective Synthesis of (S)-(Ð)-5,5,5-Trifluoro-4-Hydroxy-2-Pentanone by Baker's Yeast Reduction.

BUCCIARELLI, Maria;FORNI, Arrigo;MORETTI, Irene;PRATI, Fabio;TORRE, Giovanni
1990

Abstract

Baker's yeast reduces 1,1,1-trifluoro-2,4-pentanedione with high regio- and enantio-selectivity to give (S)-5,5,5-trifluoro-4-hydroxy-2-pentanone. The enantiomeric excess was determined by Mosher's method and the absolute configuration was established by correlation with ethyl (R)-(+)-4,4,4-trifluoro-3-hydroxybutanoate.
120
99
99
Enantioselective Synthesis of (S)-(Ð)-5,5,5-Trifluoro-4-Hydroxy-2-Pentanone by Baker's Yeast Reduction / Bucciarelli, Maria; Forni, Arrigo; Moretti, Irene; Prati, Fabio; Torre, Giovanni. - In: GAZZETTA CHIMICA ITALIANA. - ISSN 0016-5603. - STAMPA. - 120:(1990), pp. 99-99.
Bucciarelli, Maria; Forni, Arrigo; Moretti, Irene; Prati, Fabio; Torre, Giovanni
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/457192
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact