Microbial reduction with baker's yeast or Aspergillus niger of methyl 4-chloro-4,4-difluoro-3-oxobutanoate 1 afforded the optically active methyl (-)-4-chloro-4,4-difluoro-3-hydroxybutanoate 2. When yeast reduction was carried out in the presence of allyl bromide, optically active (+)-2 was obtanied.
Microbial Synthesis of Methyl (+) and (-) 4-Chloro-4,4-difluoro-3- hydroxybutanoate / Forni, Arrigo; Moretti, Irene; Prati, Fabio; Torre, Giovanni. - In: JOURNAL OF MOLECULAR CATALYSIS. A: CHEMICAL. - ISSN 1381-1169. - STAMPA. - 107:(1996), pp. 405-407.
Microbial Synthesis of Methyl (+) and (-) 4-Chloro-4,4-difluoro-3- hydroxybutanoate
FORNI, Arrigo;MORETTI, Irene;PRATI, Fabio;TORRE, Giovanni
1996
Abstract
Microbial reduction with baker's yeast or Aspergillus niger of methyl 4-chloro-4,4-difluoro-3-oxobutanoate 1 afforded the optically active methyl (-)-4-chloro-4,4-difluoro-3-hydroxybutanoate 2. When yeast reduction was carried out in the presence of allyl bromide, optically active (+)-2 was obtanied.
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
