Generalized gastrointestinal juvenile polyposis is a rare form of diffuse polyposis in which cancer infrequently develops. A clinical case is described in which gastric polyps showed a variety of histological features, including both in situ and invasive adenocarcinoma. Many mixed lesions were observed, confirming a morphological sequence already documented in colorectal tumorigenesis but still undefined in gastric tumors. The patient seems strongly predisposed to gastric cancer, presumably on a genetic basis, because he developed a malignancy in a hyperplastic juvenile polyp, usually not considered a precancerous lesion. There is no doubt that cases like this may be important for accurate genetic evaluation and biological characterization.
Generalized juvenile polyposis with mixed pattern and gastric cancer / R., Sassatelli; G., Bertoni; L., Serra; G., Bedogni; PONZ DE LEON, Maurizio. - In: GASTROENTEROLOGY. - ISSN 0016-5085. - STAMPA. - 104(1993), pp. 910-915.
Data di pubblicazione: | 1993 |
Titolo: | Generalized juvenile polyposis with mixed pattern and gastric cancer |
Autore/i: | R., Sassatelli; G., Bertoni; L., Serra; G., Bedogni; PONZ DE LEON, Maurizio |
Autore/i UNIMORE: | |
Rivista: | |
Volume: | 104 |
Pagina iniziale: | 910 |
Pagina finale: | 915 |
Codice identificativo ISI: | WOS:A1993KP44800031 |
Codice identificativo Scopus: | 2-s2.0-0027502124 |
Codice identificativo Pubmed: | 8440442 |
Citazione: | Generalized juvenile polyposis with mixed pattern and gastric cancer / R., Sassatelli; G., Bertoni; L., Serra; G., Bedogni; PONZ DE LEON, Maurizio. - In: GASTROENTEROLOGY. - ISSN 0016-5085. - STAMPA. - 104(1993), pp. 910-915. |
Tipologia | Articolo su rivista |
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