We have isolated a new chicken gene that is a member of the cysteine-rich secreted protein family (CRISP). The CRISP family is composed of over 70 members that are found in many phyla of organisms, including: vertebrates, plants, fungi, yeast, and insects. Here we describe the cloning of a novel member of this family, SugarCrisp, and its expression pattern throughout chicken embryogenesis. We also describe its utility as a marker of thyroid and pancreatic mesoderm in the developing chicken embryo and its expression within the human and mouse in glandular tissue.
Cloning and expression of a novel Cysteine-Rich Secreted Protein family member expressed in thyroid and pancreatic mesoderm within the chicken embryo / Smith, D. M.; COLLINS RACIE, L. A.; Marigo, Valeria; Roberts, D. J.; Davis, N. M.; Hartmann, C.; Schweitzer, R.; Lavallie, E. R.; Gamer, L.; Mccoy, J.; Tabin, C. J.. - In: MECHANISMS OF DEVELOPMENT. - ISSN 0925-4773. - STAMPA. - 102:(2001), pp. 223-226. [10.1016/S0925-4773(01)00293-3]