The agonist potency of 2-cia-methyl-5-dimethylaminomethyl-1,3-oxathiolane-3-traqns-oxide methiodide and its two enantiomers were detemined in vivo at muscarinic M1 and M2 receptors. The results indicate a selectivity of 5-8 fold for M1 receptors, confirming the M1 profile of the oxathiolane nucleus.

Determination of Muscarinic Agonist Potencies at M1 and M2 Receptors in Pithed Rat / Angeli, P.; Brasili, Livio; Gulini, U.; Cantalamessa, F.. - In: PHARMACEUTICAL AND PHARMACOLOGICAL LETTERS. - ISSN 0939-9488. - STAMPA. - 2:(1993), pp. 207-209.

Determination of Muscarinic Agonist Potencies at M1 and M2 Receptors in Pithed Rat

BRASILI, Livio;
1993

Abstract

The agonist potency of 2-cia-methyl-5-dimethylaminomethyl-1,3-oxathiolane-3-traqns-oxide methiodide and its two enantiomers were detemined in vivo at muscarinic M1 and M2 receptors. The results indicate a selectivity of 5-8 fold for M1 receptors, confirming the M1 profile of the oxathiolane nucleus.
1993
2
207
209
Determination of Muscarinic Agonist Potencies at M1 and M2 Receptors in Pithed Rat / Angeli, P.; Brasili, Livio; Gulini, U.; Cantalamessa, F.. - In: PHARMACEUTICAL AND PHARMACOLOGICAL LETTERS. - ISSN 0939-9488. - STAMPA. - 2:(1993), pp. 207-209.
Angeli, P.; Brasili, Livio; Gulini, U.; Cantalamessa, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/449040
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