This article has no abstract; the first 100 words appear below.For much of the 20th century, hereditary hemochromatosis was regarded as a clinically and genetically unique entity. The classic findings on presentation — diabetes, bronze pigmentation of the skin, and cirrhosis — were first described in the 19th century, when the term “hemochromatosis” was first used13; by 1935 it had become clear that the disease was hereditary and was caused by excess deposits of iron in the tissue.4 In the 1970s and 1980s, it was recognized as an autosomal recessive disorder linked to the region of the short arm of chromosome 6 encoding HLA-A*3 ,5,6 and in . . .

Hereditary hemochromatosis--a new look at an old disease / Pietrangelo, Antonello. - In: THE NEW ENGLAND JOURNAL OF MEDICINE. - ISSN 0028-4793. - STAMPA. - 350(23):(2004), pp. 2383-2397. [10.1056/NEJMra031573]

Hereditary hemochromatosis--a new look at an old disease.

PIETRANGELO, Antonello
2004

Abstract

This article has no abstract; the first 100 words appear below.For much of the 20th century, hereditary hemochromatosis was regarded as a clinically and genetically unique entity. The classic findings on presentation — diabetes, bronze pigmentation of the skin, and cirrhosis — were first described in the 19th century, when the term “hemochromatosis” was first used13; by 1935 it had become clear that the disease was hereditary and was caused by excess deposits of iron in the tissue.4 In the 1970s and 1980s, it was recognized as an autosomal recessive disorder linked to the region of the short arm of chromosome 6 encoding HLA-A*3 ,5,6 and in . . .
2004
350(23)
2383
2397
Hereditary hemochromatosis--a new look at an old disease / Pietrangelo, Antonello. - In: THE NEW ENGLAND JOURNAL OF MEDICINE. - ISSN 0028-4793. - STAMPA. - 350(23):(2004), pp. 2383-2397. [10.1056/NEJMra031573]
Pietrangelo, Antonello
File in questo prodotto:
File Dimensione Formato  
Pietrangelo-NEJM2004.pdf

Solo gestori archivio

Tipologia: Versione pubblicata dall'editore
Dimensione 684.05 kB
Formato Adobe PDF
684.05 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/4221
Citazioni
  • ???jsp.display-item.citation.pmc??? 190
  • Scopus 868
  • ???jsp.display-item.citation.isi??? 692
social impact