Introduction. Living donation in adult liver transplantation (LDLTx) is an important resource because of the waiting list growth. We. started a living donor program to overcome the shortage of cadaveric sources. Patients. From May 2001 to May 2003, 36 patients underwent LDLTx: 27 received a right lobe, 8 received a left lobe, and 1 received segments 11 and III. Results. The 1-year actuarial survival rate was 77.7%, with a mean follow-up, in survivors, of 754 +/- 248 days. Eleven of 27 (40.7%) right lobe recipients died. Among left graft recipients, 3 patients died (33%). We undertook retransplantation in 4 cases, because of 2 small for size syndrome, 1 late hepatic artery thrombosis, and 1 early portal vein thrombosis. After a period of 797 days, all 36 donors returned to a normal social and working life. Two donors, who underwent right lobe donation, experienced major complications: 1 case of biliary stenosis, treated by stenting, and I case of biliary leak from the cut surface of the liver, requiring laparotomy and abscess drainage. Left lobe donors developed no complications. Conclusions. LDLTx has a learning curve for experienced liver transplantation surgeons. Our last 18 cases showed better survivals than the first 18 (9 deaths vs 5), even if, in the latter group, we transplanted 8 left livers. In our experience, LDLTx of a left liver graft has an increased risk of small for size syndrome, but patients, both donors and recipients, report improved outcomes.

Living donor liver transplantation in adult patients : our experience / A., Dazzi; A., Lauro; DI BENEDETTO, Fabrizio; Masetti, Michele; Cautero, Nicola; N., De Ruvo; Quintini, Cristiano; G., Ramacciato; C. M., Miller; A. D., Pinna. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - STAMPA. - 37:(2005), pp. 2595-2596.

Living donor liver transplantation in adult patients : our experience.

DI BENEDETTO, Fabrizio;MASETTI, Michele;CAUTERO, Nicola;QUINTINI, Cristiano;
2005-01-01

Abstract

Introduction. Living donation in adult liver transplantation (LDLTx) is an important resource because of the waiting list growth. We. started a living donor program to overcome the shortage of cadaveric sources. Patients. From May 2001 to May 2003, 36 patients underwent LDLTx: 27 received a right lobe, 8 received a left lobe, and 1 received segments 11 and III. Results. The 1-year actuarial survival rate was 77.7%, with a mean follow-up, in survivors, of 754 +/- 248 days. Eleven of 27 (40.7%) right lobe recipients died. Among left graft recipients, 3 patients died (33%). We undertook retransplantation in 4 cases, because of 2 small for size syndrome, 1 late hepatic artery thrombosis, and 1 early portal vein thrombosis. After a period of 797 days, all 36 donors returned to a normal social and working life. Two donors, who underwent right lobe donation, experienced major complications: 1 case of biliary stenosis, treated by stenting, and I case of biliary leak from the cut surface of the liver, requiring laparotomy and abscess drainage. Left lobe donors developed no complications. Conclusions. LDLTx has a learning curve for experienced liver transplantation surgeons. Our last 18 cases showed better survivals than the first 18 (9 deaths vs 5), even if, in the latter group, we transplanted 8 left livers. In our experience, LDLTx of a left liver graft has an increased risk of small for size syndrome, but patients, both donors and recipients, report improved outcomes.
37
2595
2596
Living donor liver transplantation in adult patients : our experience / A., Dazzi; A., Lauro; DI BENEDETTO, Fabrizio; Masetti, Michele; Cautero, Nicola; N., De Ruvo; Quintini, Cristiano; G., Ramacciato; C. M., Miller; A. D., Pinna. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - STAMPA. - 37:(2005), pp. 2595-2596.
A., Dazzi; A., Lauro; DI BENEDETTO, Fabrizio; Masetti, Michele; Cautero, Nicola; N., De Ruvo; Quintini, Cristiano; G., Ramacciato; C. M., Miller; A. D., Pinna
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/310334
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