Bacteria attach to surfaces and aggregate in a biopolymer matrix to form biofilm. Studies on biofilm have shown its presence in many prosthetic devices used in nephrology as well as in fluid pathways of hemodialysis plants and monitors. Once present, this community of bacteria increases resistance to biocide due to slime production and, as a result, chemical products for dialysis monitor disinfection and descaling procedures do not result in an effective treatment. Ultrapure dialysate is a goal in modern hemodialysis, and ultrafiltration is used to obtain sterile and apyrogen fluids. Microbial colonisation of ultrafilters may occur if, due to inadequate disinfection protocols, membrane is exposed to persistent bacterial contamination, and biofilm is allowed to form and to grow. As more and more data link final dialysate microbial contamination to clinical effects of bioincompatibility from chronic inflammation in dialysis patients, attention has to be focused on possibilities of biofilm avoidance. Copyright 2000 S. Karger AG, Basel

Biofilms invade nephrology: effects in hemodialysis / Cappelli, Gianni; M., Ballestri; S., Perrone; A., Ciuffreda; P., Inguaggiato; Albertazzi, Alberto. - In: BLOOD PURIFICATION. - ISSN 0253-5068. - STAMPA. - 18 (3):(2000), pp. 224-230.

Biofilms invade nephrology: effects in hemodialysis

CAPPELLI, Gianni;ALBERTAZZI, Alberto
2000

Abstract

Bacteria attach to surfaces and aggregate in a biopolymer matrix to form biofilm. Studies on biofilm have shown its presence in many prosthetic devices used in nephrology as well as in fluid pathways of hemodialysis plants and monitors. Once present, this community of bacteria increases resistance to biocide due to slime production and, as a result, chemical products for dialysis monitor disinfection and descaling procedures do not result in an effective treatment. Ultrapure dialysate is a goal in modern hemodialysis, and ultrafiltration is used to obtain sterile and apyrogen fluids. Microbial colonisation of ultrafilters may occur if, due to inadequate disinfection protocols, membrane is exposed to persistent bacterial contamination, and biofilm is allowed to form and to grow. As more and more data link final dialysate microbial contamination to clinical effects of bioincompatibility from chronic inflammation in dialysis patients, attention has to be focused on possibilities of biofilm avoidance. Copyright 2000 S. Karger AG, Basel
18 (3)
224
230
Biofilms invade nephrology: effects in hemodialysis / Cappelli, Gianni; M., Ballestri; S., Perrone; A., Ciuffreda; P., Inguaggiato; Albertazzi, Alberto. - In: BLOOD PURIFICATION. - ISSN 0253-5068. - STAMPA. - 18 (3):(2000), pp. 224-230.
Cappelli, Gianni; M., Ballestri; S., Perrone; A., Ciuffreda; P., Inguaggiato; Albertazzi, Alberto
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/310229
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 37
  • ???jsp.display-item.citation.isi??? 35
social impact