The purpose of this work was to evaluate the bioadhesive properties of microspheres based on sodium alginate and BSA prepd. by a spray-drying technique. The microspheres were cross-linked using a two steps process with calcium chloride and various amts. of chitosan. The bioadhesiveness of these systems was evaluated using a "ex vivo" method that allowed quant. results to be drawn. It was concluded that the crosslinking step using different amts. of chitosan, even if involved the sites implicated in the bioadhesive process, did not modified the good bioadhesiveness of the calcium alginate microspheres.

Evaluation of bioadhesive properties of microspheres using an "ex vivo" test / Leo, Eliana Grazia; Coppi, Gilberto; Guerra, Paolo; Vandelli, Maria Angela; Cameroni, Riccardo. - In: ACTA TECHNOLOGIAE ET LEGIS MEDICAMENTI. - ISSN 1121-2098. - STAMPA. - 12:(2001), pp. 17-26.

Evaluation of bioadhesive properties of microspheres using an "ex vivo" test

LEO, Eliana Grazia;COPPI, Gilberto;GUERRA, Paolo;VANDELLI, Maria Angela;CAMERONI, Riccardo
2001-01-01

Abstract

The purpose of this work was to evaluate the bioadhesive properties of microspheres based on sodium alginate and BSA prepd. by a spray-drying technique. The microspheres were cross-linked using a two steps process with calcium chloride and various amts. of chitosan. The bioadhesiveness of these systems was evaluated using a "ex vivo" method that allowed quant. results to be drawn. It was concluded that the crosslinking step using different amts. of chitosan, even if involved the sites implicated in the bioadhesive process, did not modified the good bioadhesiveness of the calcium alginate microspheres.
12
17
26
Evaluation of bioadhesive properties of microspheres using an "ex vivo" test / Leo, Eliana Grazia; Coppi, Gilberto; Guerra, Paolo; Vandelli, Maria Angela; Cameroni, Riccardo. - In: ACTA TECHNOLOGIAE ET LEGIS MEDICAMENTI. - ISSN 1121-2098. - STAMPA. - 12:(2001), pp. 17-26.
Leo, Eliana Grazia; Coppi, Gilberto; Guerra, Paolo; Vandelli, Maria Angela; Cameroni, Riccardo
File in questo prodotto:
File Dimensione Formato  
2001 Acta legis Leo e Coppi.pdf

Accesso riservato

Tipologia: Versione pubblicata dall'editore
Dimensione 3.12 MB
Formato Adobe PDF
3.12 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/307527
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact