The study aim is to describe the long-term clinical outcome of 102 chronic headache patients with analgesic daily use. They were assessed for daily drug intake (DDT), headache index (HI) and quality of life (QoL) and compared with a parallel group of patients with active chronic daily headache but no analgesic overuse. For the primary study group, baseline 1995 DDT was 1.80 +/-1.87 and did not differ significantly in 1999. Patients who daily continued to use analgesics had a higher 1995 baseline DDT (t=2.275, P=0.025), a longer drug abuse history (t=2.282, P=0.025) and a higher DDT (t=4.042, P<0.001) 4 years later. At 4 years of follow-up, only one-third of patients initially treated for chronic daily headache and analgesic overuse are successful in refraining from chronic overuse. Those subjects appear to have a persistence for combination analgesic agents; however, their QoL is slightly better than that of patients who revert to episodic headache or continue with chronic daily headache but do not overuse analgesic agents. Persistent analgesic overuse seems to be linked to the length of abuse and to the number of drugs ingested.

Long-term follow-up of patients treated for chronic headache with analgesic overuse / Pini, Luigi Alberto; Afg, Cicero; Sandrini, Maurizio. - In: CEPHALALGIA. - ISSN 0333-1024. - STAMPA. - 21:9(2001), pp. 878-883. [10.1046/j.1468-2982.2001.00288.x]

Long-term follow-up of patients treated for chronic headache with analgesic overuse

PINI, Luigi Alberto;SANDRINI, Maurizio
2001

Abstract

The study aim is to describe the long-term clinical outcome of 102 chronic headache patients with analgesic daily use. They were assessed for daily drug intake (DDT), headache index (HI) and quality of life (QoL) and compared with a parallel group of patients with active chronic daily headache but no analgesic overuse. For the primary study group, baseline 1995 DDT was 1.80 +/-1.87 and did not differ significantly in 1999. Patients who daily continued to use analgesics had a higher 1995 baseline DDT (t=2.275, P=0.025), a longer drug abuse history (t=2.282, P=0.025) and a higher DDT (t=4.042, P<0.001) 4 years later. At 4 years of follow-up, only one-third of patients initially treated for chronic daily headache and analgesic overuse are successful in refraining from chronic overuse. Those subjects appear to have a persistence for combination analgesic agents; however, their QoL is slightly better than that of patients who revert to episodic headache or continue with chronic daily headache but do not overuse analgesic agents. Persistent analgesic overuse seems to be linked to the length of abuse and to the number of drugs ingested.
2001
21
9
878
883
Long-term follow-up of patients treated for chronic headache with analgesic overuse / Pini, Luigi Alberto; Afg, Cicero; Sandrini, Maurizio. - In: CEPHALALGIA. - ISSN 0333-1024. - STAMPA. - 21:9(2001), pp. 878-883. [10.1046/j.1468-2982.2001.00288.x]
Pini, Luigi Alberto; Afg, Cicero; Sandrini, Maurizio
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/307340
Citazioni
  • ???jsp.display-item.citation.pmc??? 9
  • Scopus 96
  • ???jsp.display-item.citation.isi??? 69
social impact