Lipospheres for the cosmetic delivery of glycolic acid were prepared by the melt method using tristearin as the lipid phase and hydrogenated soybean phosphatidylcholine as the emulsifier. The lipospheres, sized from 5 to 40 micron, contained a rather high glycolic acid loading level probably due to a partial polymorphic modification of the lipid and determined glycolic acid sustained release pattern.
Preparation and in vitro characterization of lipospheres as a carrier for the cosmetic application of glycolic acid / Iannuccelli, Valentina; Coppi, Gilberto; Sergi, Santo; Cameroni, Riccardo. - In: JOURNAL OF APPLIED COSMETOLOGY. - ISSN 0392-8543. - STAMPA. - 19:4(2001), pp. 113-119.
Preparation and in vitro characterization of lipospheres as a carrier for the cosmetic application of glycolic acid
IANNUCCELLI, Valentina;COPPI, Gilberto;SERGI, Santo;CAMERONI, Riccardo
2001
Abstract
Lipospheres for the cosmetic delivery of glycolic acid were prepared by the melt method using tristearin as the lipid phase and hydrogenated soybean phosphatidylcholine as the emulsifier. The lipospheres, sized from 5 to 40 micron, contained a rather high glycolic acid loading level probably due to a partial polymorphic modification of the lipid and determined glycolic acid sustained release pattern.
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