EnglishIfenprodil - an antagonist at the modulatory site of the NMDA receptor complex sensitive to polyamines - intraperitoneally injected at doses of 3 or 10 mg/kg, dose dependently prevented the behavioral syndrome induced by intracerebroventricular administration of adrenocorticotropin (ACTH)-(1-24) in adult male rats (excessive grooming, stretching, yawning, penile erections). These data further support a role of the brain ornithine decarboxylase (ODC)-polyamine system in the ACTH-induced behavioral syndrome, and may suggest an involvement of excitatory amino acids.
Influence of ifenprodil on the ACTH-induced behavioral syndrome in rats / Genedani, Susanna; M., Bernardi; Bertolini, Alfio. - In: EUROPEAN JOURNAL OF PHARMACOLOGY. - ISSN 0014-2999. - STAMPA. - 252(1994), pp. 77-80.
| Data di pubblicazione: | 1994 |
| Titolo: | Influence of ifenprodil on the ACTH-induced behavioral syndrome in rats |
| Autore/i: | Genedani, Susanna; M., Bernardi; Bertolini, Alfio |
| Autore/i UNIMORE: | |
| Rivista: | |
| Volume: | 252 |
| Pagina iniziale: | 77 |
| Pagina finale: | 80 |
| Codice identificativo ISI: | WOS:A1994MV09900010 |
| Codice identificativo Scopus: | 2-s2.0-0028103734 |
| Codice identificativo Pubmed: | 8149997 |
| Citazione: | Influence of ifenprodil on the ACTH-induced behavioral syndrome in rats / Genedani, Susanna; M., Bernardi; Bertolini, Alfio. - In: EUROPEAN JOURNAL OF PHARMACOLOGY. - ISSN 0014-2999. - STAMPA. - 252(1994), pp. 77-80. |
| Tipologia | Articolo su rivista |
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