BACKGROUND: Seasons may influence prenatal growth and future fertility. This study investigated whether season and month of birth influenced the timing of menopause in a group of women attending three Italian menopause clinics. METHODS andRESULTS: Age at menopause of 2822 post-menopausal women (>12 months of amenorrhoea) was stratified by month and season of birth. Mean age at menopause was 49.42 years (SEM: 0.78 years). Menopause occurred earlier for women born in the spring (age 49.04+/-0.15 years) than in the autumn (49.97+/-0.14 years). The earliest menopause was found in women born in March (48.9+/-0.25 years) and the latest in women born in October (50.3+/-0.25 years). The effect of season of birth on age at menopause remained even when considering factors that in our analysis were capable of significantly interfering with the timing of menopause, such as age at menarche, body mass index, smoking habit, level of education and type of job.CONCLUSIONS: Taking into consideration the retrospective design of the study, and a possible recall bias, the present data seem to suggest that environmental factors linked to seasons are capable of interfering with the timing of a woman's ovarian exhaustion by an action exerted in the prenatal period.

Season of birth influences the timing of menopause / Cagnacci, Angelo; Pansini, Fs; Bacchi Modena, A; Giulini, N; Mollica, G; De Aloysio, D; Vadora, E; Volpe, Annibale. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - STAMPA. - 20:(2005), pp. 2190-2193.

Season of birth influences the timing of menopause

CAGNACCI, Angelo;VOLPE, Annibale
2005

Abstract

BACKGROUND: Seasons may influence prenatal growth and future fertility. This study investigated whether season and month of birth influenced the timing of menopause in a group of women attending three Italian menopause clinics. METHODS andRESULTS: Age at menopause of 2822 post-menopausal women (>12 months of amenorrhoea) was stratified by month and season of birth. Mean age at menopause was 49.42 years (SEM: 0.78 years). Menopause occurred earlier for women born in the spring (age 49.04+/-0.15 years) than in the autumn (49.97+/-0.14 years). The earliest menopause was found in women born in March (48.9+/-0.25 years) and the latest in women born in October (50.3+/-0.25 years). The effect of season of birth on age at menopause remained even when considering factors that in our analysis were capable of significantly interfering with the timing of menopause, such as age at menarche, body mass index, smoking habit, level of education and type of job.CONCLUSIONS: Taking into consideration the retrospective design of the study, and a possible recall bias, the present data seem to suggest that environmental factors linked to seasons are capable of interfering with the timing of a woman's ovarian exhaustion by an action exerted in the prenatal period.
20
2190
2193
Season of birth influences the timing of menopause / Cagnacci, Angelo; Pansini, Fs; Bacchi Modena, A; Giulini, N; Mollica, G; De Aloysio, D; Vadora, E; Volpe, Annibale. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - STAMPA. - 20:(2005), pp. 2190-2193.
Cagnacci, Angelo; Pansini, Fs; Bacchi Modena, A; Giulini, N; Mollica, G; De Aloysio, D; Vadora, E; Volpe, Annibale
File in questo prodotto:
File Dimensione Formato  
HumaRep Menopause.pdf

non disponibili

Tipologia: Post-print dell'autore (bozza post referaggio)
Dimensione 181.25 kB
Formato Adobe PDF
181.25 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/305844
Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 34
  • ???jsp.display-item.citation.isi??? 27
social impact