Immunocytochemical methods were used to study the presence and distribution of IL-1-alpha- and TNF-alpha -like molecules in the hemocytes of the colonial ascidian Botryllus schlosseri. Only a few unstimulated hemocytes were positive to both the antibodies used. When the hemocytes were stimulated with either mannan or phorbol 12-mono-myristate, the phagocytes were not significantly changed in their number, staining intensity, or cell morphology. In contrast, stimulated morula cells were intensely labeled, indicating that these cells play an important immunomodulatory role.

Morula cells as the major immunomodulatory hemocytes in ascidians: evidences from the colonial species Botryllus schlosseri / L., Ballarin; Franchini, Antonella; Ottaviani, Enzo; A., Sabbadin. - In: THE BIOLOGICAL BULLETIN. - ISSN 0006-3185. - STAMPA. - 201:(2001), pp. 59-64.

Morula cells as the major immunomodulatory hemocytes in ascidians: evidences from the colonial species Botryllus schlosseri

FRANCHINI, Antonella;OTTAVIANI, Enzo;
2001

Abstract

Immunocytochemical methods were used to study the presence and distribution of IL-1-alpha- and TNF-alpha -like molecules in the hemocytes of the colonial ascidian Botryllus schlosseri. Only a few unstimulated hemocytes were positive to both the antibodies used. When the hemocytes were stimulated with either mannan or phorbol 12-mono-myristate, the phagocytes were not significantly changed in their number, staining intensity, or cell morphology. In contrast, stimulated morula cells were intensely labeled, indicating that these cells play an important immunomodulatory role.
201
59
64
Morula cells as the major immunomodulatory hemocytes in ascidians: evidences from the colonial species Botryllus schlosseri / L., Ballarin; Franchini, Antonella; Ottaviani, Enzo; A., Sabbadin. - In: THE BIOLOGICAL BULLETIN. - ISSN 0006-3185. - STAMPA. - 201:(2001), pp. 59-64.
L., Ballarin; Franchini, Antonella; Ottaviani, Enzo; A., Sabbadin
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/305396
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