Enantiomeric (R)- and (S)-2-aminopropanesulfonic acids, 4a and 4b, were prepared in good yields and high enantiomeric purities (>99% ee) from (S)-5a and (R)-1-amino-2-propanol 5b respectively, using a four step synthesis. The absolute configuration of(S)-enantiomer 4b was established by X-ray analysis.
Asymmetric synthesis of 2-methyltaurine / Braghiroli, Daniela; E., Mussati; M., DI BELLA; Saladini, Monica. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - STAMPA. - 7:(1996), pp. 831-836.
Asymmetric synthesis of 2-methyltaurine
BRAGHIROLI, Daniela;SALADINI, Monica
1996
Abstract
Enantiomeric (R)- and (S)-2-aminopropanesulfonic acids, 4a and 4b, were prepared in good yields and high enantiomeric purities (>99% ee) from (S)-5a and (R)-1-amino-2-propanol 5b respectively, using a four step synthesis. The absolute configuration of(S)-enantiomer 4b was established by X-ray analysis.
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