This is the report of the 55th of a series of workshopsorganised by the European Centre for theValidation of Alternative Methods (ECVAM). Themain objective of ECVAM, as defined in 1993 by itsScientific Advisory Committee, is to promote thescientific and regulatory acceptance of alternativemethods which are of importance to the biosciences,and which reduce, refine or replace the use of laboratoryanimals. One of the first priorities set byECVAM was the implementation of procedures thatwould enable it to become well informed about thestatus of non-animal test development and validation,and of opportunities for the possible incorporationof alternative methods into regulatoryprocedures. It was decided that this would beachieved through a programme of ECVAM workshops,each addressing a specific topic, and at whichselected groups of independent internationalexperts would review the current status of varioustypes of in vitro tests and their potential uses, andmake recommendations about the best ways forward(1).The workshop on Three Rs Approaches in MarineBiotoxin Testing was held at ECVAM on 24–26January 2005, with participants from academia,national and international reference laboratories,competent authorities and the European Commission(EC). This ECVAM/DG SANCO Workshopwas organised: a) to discuss the current state-ofthe-art with regard to test methods and strategies;b) to consider immediate opportunities to reduceand refine animal use; and c) to examine the possibilitiesof validation and acceptance of non-animalmethods as monitoring tools and reference methodsin marine biotoxin testing, reflecting the technicalprogress that had been made. The outcome of thediscussions and the recommendations agreed by theworkshop participants are summarised in thisreport, which is primarily focused on the situation

Three Rs approaches in marine biotoxin testing - The report and recommendations of a joint ECVAM/DG SANCO workshop (ECVAM workshop 55) / P., Hess; B., Grune; Db, Anderson; T., Aune; Lm, Botana; P., Caricato; HP van, Egmond; M., Halder; S., Hall; Jf, Lawrence; C., Moffat; R., Poletti; J., Richmond; Rossini, Gian Paolo; C., Seamer; Js, Vilageliu. - In: ATLA. ALTERNATIVES TO LABORATORY ANIMALS. - ISSN 0261-1929. - STAMPA. - 34:(2006), pp. 193-224.

Three Rs approaches in marine biotoxin testing - The report and recommendations of a joint ECVAM/DG SANCO workshop (ECVAM workshop 55)

ROSSINI, Gian Paolo;
2006

Abstract

This is the report of the 55th of a series of workshopsorganised by the European Centre for theValidation of Alternative Methods (ECVAM). Themain objective of ECVAM, as defined in 1993 by itsScientific Advisory Committee, is to promote thescientific and regulatory acceptance of alternativemethods which are of importance to the biosciences,and which reduce, refine or replace the use of laboratoryanimals. One of the first priorities set byECVAM was the implementation of procedures thatwould enable it to become well informed about thestatus of non-animal test development and validation,and of opportunities for the possible incorporationof alternative methods into regulatoryprocedures. It was decided that this would beachieved through a programme of ECVAM workshops,each addressing a specific topic, and at whichselected groups of independent internationalexperts would review the current status of varioustypes of in vitro tests and their potential uses, andmake recommendations about the best ways forward(1).The workshop on Three Rs Approaches in MarineBiotoxin Testing was held at ECVAM on 24–26January 2005, with participants from academia,national and international reference laboratories,competent authorities and the European Commission(EC). This ECVAM/DG SANCO Workshopwas organised: a) to discuss the current state-ofthe-art with regard to test methods and strategies;b) to consider immediate opportunities to reduceand refine animal use; and c) to examine the possibilitiesof validation and acceptance of non-animalmethods as monitoring tools and reference methodsin marine biotoxin testing, reflecting the technicalprogress that had been made. The outcome of thediscussions and the recommendations agreed by theworkshop participants are summarised in thisreport, which is primarily focused on the situation
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193
224
Three Rs approaches in marine biotoxin testing - The report and recommendations of a joint ECVAM/DG SANCO workshop (ECVAM workshop 55) / P., Hess; B., Grune; Db, Anderson; T., Aune; Lm, Botana; P., Caricato; HP van, Egmond; M., Halder; S., Hall; Jf, Lawrence; C., Moffat; R., Poletti; J., Richmond; Rossini, Gian Paolo; C., Seamer; Js, Vilageliu. - In: ATLA. ALTERNATIVES TO LABORATORY ANIMALS. - ISSN 0261-1929. - STAMPA. - 34:(2006), pp. 193-224.
P., Hess; B., Grune; Db, Anderson; T., Aune; Lm, Botana; P., Caricato; HP van, Egmond; M., Halder; S., Hall; Jf, Lawrence; C., Moffat; R., Poletti; J., Richmond; Rossini, Gian Paolo; C., Seamer; Js, Vilageliu
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/305289
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