Two cases of placental transmogrification of the lung are reported. The lesions presented in the left lung, in one case as a giant bulla of the upper lobe and in the other as a cystic nodule of the lower lobe. A segmentectomy was performed in both cases, and the patients were alive and well 5 years and 2 months after surgery, respectively. In our opinion. pulmonary placental transmogrification is not a variant of emphysema, as generally considered, but rather probably represents a benign proliferation of immature interstitial clear cells with secondary cystic change. This report presents a histological, immunohistochemical, ultrastructural and molecular study of these peculiar cells, together with a review of the literature.

Placental transmogrification of the lung: Clinicopathologic, immunohistochemical and molecular study of two cases, with particular emphasis on the interstitial clear cells / A., Cavazza; S., Lantuejoul; Sartori, Giuliana; N., Bigiani; Maiorana, Antonino; G., Pasquinelli; Paci, Massimiliano; Rossi, Giulio. - In: HUMAN PATHOLOGY. - ISSN 0046-8177. - STAMPA. - 35:(2004), pp. 517-521.

Placental transmogrification of the lung: Clinicopathologic, immunohistochemical and molecular study of two cases, with particular emphasis on the interstitial clear cells

SARTORI, Giuliana;MAIORANA, Antonino;PACI, Massimiliano;ROSSI, Giulio
2004-01-01

Abstract

Two cases of placental transmogrification of the lung are reported. The lesions presented in the left lung, in one case as a giant bulla of the upper lobe and in the other as a cystic nodule of the lower lobe. A segmentectomy was performed in both cases, and the patients were alive and well 5 years and 2 months after surgery, respectively. In our opinion. pulmonary placental transmogrification is not a variant of emphysema, as generally considered, but rather probably represents a benign proliferation of immature interstitial clear cells with secondary cystic change. This report presents a histological, immunohistochemical, ultrastructural and molecular study of these peculiar cells, together with a review of the literature.
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Placental transmogrification of the lung: Clinicopathologic, immunohistochemical and molecular study of two cases, with particular emphasis on the interstitial clear cells / A., Cavazza; S., Lantuejoul; Sartori, Giuliana; N., Bigiani; Maiorana, Antonino; G., Pasquinelli; Paci, Massimiliano; Rossi, Giulio. - In: HUMAN PATHOLOGY. - ISSN 0046-8177. - STAMPA. - 35:(2004), pp. 517-521.
A., Cavazza; S., Lantuejoul; Sartori, Giuliana; N., Bigiani; Maiorana, Antonino; G., Pasquinelli; Paci, Massimiliano; Rossi, Giulio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/305206
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