Laccases from different sources have been used, for the first time, for the selective oxidation of the stilbenic phytoalexin transresveratrol (3,5,4´-trihydroxystilbene, 1a) on a preparative scale. Specifically, the enzymes from Myceliophtora thermophyla and from Trametes pubescens gave the dehydrodimer 2a in 31 and 18% isolated yields, respectively. These results compare favorably with the reported data for the chemically catalyzed dimerization of la (18% yields). The antioxidant properties of 2a have also been investigated.

Biotransformation of resveratrol: synthesis of trans-dehydrodimers catalyzed by laccases from Myceliophtora thermophyla and from Trametes pubescens / S., Nicotra; Cramarossa, Maria Rita; Mucci, Adele; Pagnoni, Ugo Maria; S., Riva; Forti, Luca. - In: TETRAHEDRON. - ISSN 0040-4020. - STAMPA. - 60:(2004), pp. 595-600. [10.1016/j.tet.2003.10.117]

Biotransformation of resveratrol: synthesis of trans-dehydrodimers catalyzed by laccases from Myceliophtora thermophyla and from Trametes pubescens

CRAMAROSSA, Maria Rita;MUCCI, Adele;PAGNONI, Ugo Maria;FORTI, Luca
2004

Abstract

Laccases from different sources have been used, for the first time, for the selective oxidation of the stilbenic phytoalexin transresveratrol (3,5,4´-trihydroxystilbene, 1a) on a preparative scale. Specifically, the enzymes from Myceliophtora thermophyla and from Trametes pubescens gave the dehydrodimer 2a in 31 and 18% isolated yields, respectively. These results compare favorably with the reported data for the chemically catalyzed dimerization of la (18% yields). The antioxidant properties of 2a have also been investigated.
2004
60
595
600
Biotransformation of resveratrol: synthesis of trans-dehydrodimers catalyzed by laccases from Myceliophtora thermophyla and from Trametes pubescens / S., Nicotra; Cramarossa, Maria Rita; Mucci, Adele; Pagnoni, Ugo Maria; S., Riva; Forti, Luca. - In: TETRAHEDRON. - ISSN 0040-4020. - STAMPA. - 60:(2004), pp. 595-600. [10.1016/j.tet.2003.10.117]
S., Nicotra; Cramarossa, Maria Rita; Mucci, Adele; Pagnoni, Ugo Maria; S., Riva; Forti, Luca
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/304175
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