Fibroelastolytic papulosis (FEP) is an extremely rare condition that has been documented in both women and men, all older than 40 years at the time of presentation. Histology is characterized by normal, decreased, or absent elastic fibers in the papillary dermis sometimes accompanied by a thickening of collagen fibers. The pathogenesis of FEP is unknown. However, it is believed that FEP is related to intrinsic aging. Few clinical case are presented and discussed and based on the clinical and histologic overlap in these and previous cases designated as PXE-PDE and WFPN, we believe these diseases are best described under the rubric of FEP.
Fibroelastolytic papulosis / J., Jagdeo; N. G., C; Ronchetti, Ivonne; C., Wilkel; L., Bercovitch; L., Robinson Bostom. - In: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. - ISSN 0190-9622. - STAMPA. - 51:6(2004), pp. 958-964. [10.1016/j.jaad.2004.06.038]
Fibroelastolytic papulosis
RONCHETTI, Ivonne;
2004
Abstract
Fibroelastolytic papulosis (FEP) is an extremely rare condition that has been documented in both women and men, all older than 40 years at the time of presentation. Histology is characterized by normal, decreased, or absent elastic fibers in the papillary dermis sometimes accompanied by a thickening of collagen fibers. The pathogenesis of FEP is unknown. However, it is believed that FEP is related to intrinsic aging. Few clinical case are presented and discussed and based on the clinical and histologic overlap in these and previous cases designated as PXE-PDE and WFPN, we believe these diseases are best described under the rubric of FEP.Pubblicazioni consigliate
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