The induction of anti-microbial peptides against Gram positive and negative bacteria in the IZD-MB-0503 cell line from the lepidopteranMamestra brassicae is demonstrated, while no anti-fungal activity is detected. The identification of a defensin-like molecule active againstGram positive bacteria is described for the first time in Lepidoptera. This molecule shows between 43% and 59% homology with group Adefensins from other dipteran and hymenopteran species.
The induction of anti-microbial peptides against Gram positive and negative bacteria in the IZD-MB-0503 cell line from the lepidopteran Mamestra brassicae is demonstrated, while no anti-fungal activity is detected. The identification of a defensin-like molecule active against Gram positive bacteria is described for the first time in Lepidoptera. This molecule shows between 43% and 59% homology with group A defensins from other dipteran and hymenopteran species.
Molecular characterization of a defensin in the IZD-MB-0503 cell line derived from immunocytes of the insect Mamestra brassicae (Lepidoptera) / Mandrioli, Mauro; S., Bugli; Genedani, Susanna; Ottaviani, Enzo; Saltini, S.. - In: BIOLOGY OF THE CELL. - ISSN 0248-4900. - STAMPA. - 95:1(2003), pp. 53-57. [10.1016/S0248-4900(02)01219-4]
Molecular characterization of a defensin in the IZD-MB-0503 cell line derived from immunocytes of the insect Mamestra brassicae (Lepidoptera)
MANDRIOLI, Mauro;GENEDANI, Susanna;OTTAVIANI, Enzo;
2003
Abstract
The induction of anti-microbial peptides against Gram positive and negative bacteria in the IZD-MB-0503 cell line from the lepidopteran Mamestra brassicae is demonstrated, while no anti-fungal activity is detected. The identification of a defensin-like molecule active against Gram positive bacteria is described for the first time in Lepidoptera. This molecule shows between 43% and 59% homology with group A defensins from other dipteran and hymenopteran species.
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