Female pseudohermaphroditism is a condition characterized by various degree of external genitalia virilization in a patient with female internal genitalia and karyotype (XX). External genitalia is masculinized congenitally when female fetus is exposed to excess androgenic environment. Fetal metabolic abnormalities, like congenital adrenal hyperplasia, are the most common causes of female pseudohermaphroditism, however there is a low incidence of gestational hyperandrogenism caused by maternal pathology. We report a case of female pseudohermaphroditism secondary to a maternal ovarian luteoma of pregnancy producing androgenic hormones. The newborn presented a severe degree of external genitalia virilization with high urogenital sinus (stage Prader V). Moreover we describe the main steps of diagnostic iter that are necessary both to exclude other causes of virilization and to study all anatomical aspects in view of the surgical correction. The operation consists in two phases of action: an early clitorisvulvoplasty according to Passerini-Glazel and a late vaginal pull-through with anterior saggital transanorectal approach (

A case of female pseudohermaphroditism caused by maternal androluteoma / Gallo, C.; Pancaldi, M.; Gargano, G.; Ceccarelli, Pl; Biondini, D.; Cattani, S.; Rota, C.; De Caris, V.; Bernasconi, S.; Iughetti, Lorenzo; Ferrari, Fabrizio; Cavazzuti, G. B.. - In: ACTA BIO-MEDICA DE L'ATENEO PARMENSE. - ISSN 0392-4203. - STAMPA. - 71 (S1):(2000), pp. 767-767.

A case of female pseudohermaphroditism caused by maternal androluteoma

IUGHETTI, Lorenzo;FERRARI, Fabrizio;
2000

Abstract

Female pseudohermaphroditism is a condition characterized by various degree of external genitalia virilization in a patient with female internal genitalia and karyotype (XX). External genitalia is masculinized congenitally when female fetus is exposed to excess androgenic environment. Fetal metabolic abnormalities, like congenital adrenal hyperplasia, are the most common causes of female pseudohermaphroditism, however there is a low incidence of gestational hyperandrogenism caused by maternal pathology. We report a case of female pseudohermaphroditism secondary to a maternal ovarian luteoma of pregnancy producing androgenic hormones. The newborn presented a severe degree of external genitalia virilization with high urogenital sinus (stage Prader V). Moreover we describe the main steps of diagnostic iter that are necessary both to exclude other causes of virilization and to study all anatomical aspects in view of the surgical correction. The operation consists in two phases of action: an early clitorisvulvoplasty according to Passerini-Glazel and a late vaginal pull-through with anterior saggital transanorectal approach (
71 (S1)
767
767
A case of female pseudohermaphroditism caused by maternal androluteoma / Gallo, C.; Pancaldi, M.; Gargano, G.; Ceccarelli, Pl; Biondini, D.; Cattani, S.; Rota, C.; De Caris, V.; Bernasconi, S.; Iughetti, Lorenzo; Ferrari, Fabrizio; Cavazzuti, G. B.. - In: ACTA BIO-MEDICA DE L'ATENEO PARMENSE. - ISSN 0392-4203. - STAMPA. - 71 (S1):(2000), pp. 767-767.
Gallo, C.; Pancaldi, M.; Gargano, G.; Ceccarelli, Pl; Biondini, D.; Cattani, S.; Rota, C.; De Caris, V.; Bernasconi, S.; Iughetti, Lorenzo; Ferrari, Fabrizio; Cavazzuti, G. B.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/17374
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