munoglobulinemia)or more immunoglobulins (mixedcryoglobulinemia), which precipitate at temperaturesbelow 37 °C and redissolve on re-warming is termed“cryoglobulinemia.” This is an in vitro phenomenon; theactual mechanism(s) of cryoprecipitation remains obscure.It could be secondary to intrinsic characteristics ofboth mono- and polyclonal immunoglobulin (Ig) components;it can be caused as well by the interaction amongsingle components of the cryoprecipitate.
HCV and cryoglobulinemic vasculitis / Ferri, Clodoveo; Zignego, Al; Giuggioli, D; Sebastiani, Marco; Cazzato, M; Antonelli, A; La Civita, L; Fadda, P; Longombardo, G; Pileri, S.. - In: CLEVELAND CLINIC JOURNAL OF MEDICINE. - ISSN 0891-1150. - STAMPA. - 69:(2002), pp. 1120-1123.
HCV and cryoglobulinemic vasculitis.
FERRI, Clodoveo;Giuggioli D;SEBASTIANI, Marco;
2002
Abstract
munoglobulinemia)or more immunoglobulins (mixedcryoglobulinemia), which precipitate at temperaturesbelow 37 °C and redissolve on re-warming is termed“cryoglobulinemia.” This is an in vitro phenomenon; theactual mechanism(s) of cryoprecipitation remains obscure.It could be secondary to intrinsic characteristics ofboth mono- and polyclonal immunoglobulin (Ig) components;it can be caused as well by the interaction amongsingle components of the cryoprecipitate.
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