AIMS:Newborns affected by congenital diaphragmatic hernia (CDH) are high-risk patients: today the mortality is still elevated and is essentially due to severe pulmonary hypoplasia, pulmonary hypertension and the absence of surfactant. High-Frequency Oscillatory Ventilation (HFOV) seems to be a good pre- and postoperative technique in cases of CDH.PATIENTS AND METHODS:We report our experience in the treatment of CDH; since 1987 we have followed 44 patients. We divided them into two different groups in accordance with the ventilation technique used: Group I (1987-1994): 25 patients treated with conventional mechanical ventilation (CMV); Group II (1994-1997): 19 patients treated with HFOV used since the first day of life until clinical stabilisation and also prolonged during surgery and in the postoperative period.RESULTS:37 patients (84%) underwent surgery with closure of the diaphragmatic defect. We had a very good improvement in survival, rising from 67% (CMV) to 94% (HFOV) of the patients operated on, reaching an overall survival of 56% vs 79%.CONCLUSIONS:The use of HFOV for the treatment of CDH has proved to be a valuable technique for pre-operative stabilisation and for intra- and postoperative respiratory treatment, above all for newborns with CDH.
|Data di pubblicazione:||2001|
|Titolo:||High frequency oscillatory ventilation versus conventional mechanical ventilation in congenital diaphragmatic hernia.|
|Autore/i:||Cacciari, Alfredo; Ruggeri, G.; Mordenti, M.; Ceccarelli, P. L.; Baccarini, E.; Pigna, A.; Gentili, A.|
|Codice identificativo ISI:||WOS:000168262800001|
|Codice identificativo Scopus:||2-s2.0-0035040438|
|Codice identificativo Pubmed:||11370980|
|Citazione:||High frequency oscillatory ventilation versus conventional mechanical ventilation in congenital diaphragmatic hernia / Cacciari, Alfredo; Ruggeri, G.; Mordenti, M.; Ceccarelli, P. L.; Baccarini, E.; Pigna, A.; Gentili, A.. - In: EUROPEAN JOURNAL OF PEDIATRIC SURGERY. - ISSN 0939-7248. - STAMPA. - 11(2001), pp. 3-7.|
|Tipologia||Articolo su rivista|
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