Primary lung neuroendocrine tumors (NETs) represent a rare but diverse set of neoplasms occurring with increasing frequency. Well-differentiated NETs, also known as bronchial carcinoids, are classified as either typical carcinoids or intermediate-grade atypical carcinoids and are best treated with formal anatomic lung resection with systematic lymphadenectomy. Small-cell and large-cell neuroendocrine carcinomas represent more aggressive histologies though surgical resection with adjuvant chemotherapy remains the standard approach for well-selected patients with localized disease. This chapter reviews the diagnosis and surgical management of primary lung NETs.
Primary neuroendocrine tumors of the lung / Filosso, P. L.; Fontana, E. C.; Roffinella, M.. - (2021), pp. 209-222. [10.1007/978-3-030-62241-1_13]
Primary neuroendocrine tumors of the lung
Filosso P. L.;
2021
Abstract
Primary lung neuroendocrine tumors (NETs) represent a rare but diverse set of neoplasms occurring with increasing frequency. Well-differentiated NETs, also known as bronchial carcinoids, are classified as either typical carcinoids or intermediate-grade atypical carcinoids and are best treated with formal anatomic lung resection with systematic lymphadenectomy. Small-cell and large-cell neuroendocrine carcinomas represent more aggressive histologies though surgical resection with adjuvant chemotherapy remains the standard approach for well-selected patients with localized disease. This chapter reviews the diagnosis and surgical management of primary lung NETs.
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