Primary lung neuroendocrine tumors (NETs) represent a rare but diverse set of neoplasms occurring with increasing frequency. Well-differentiated NETs, also known as bronchial carcinoids, are classified as either typical carcinoids or intermediate-grade atypical carcinoids and are best treated with formal anatomic lung resection with systematic lymphadenectomy. Small-cell and large-cell neuroendocrine carcinomas represent more aggressive histologies though surgical resection with adjuvant chemotherapy remains the standard approach for well-selected patients with localized disease. This chapter reviews the diagnosis and surgical management of primary lung NETs.
Primary neuroendocrine tumors of the lung / Filosso, P.L., Fontana, E.C., Roffinella, M. - In: Neuroendocrine Tumors. Surgical Evaluation and Management / [a cura di] Jordan M. Cloyd, Timothy M. Pawlik. - [s.l], 2021. - ISBN 9783030622404. - pp. 209-222 [10.1007/978-3-030-62241-1_13]
Primary neuroendocrine tumors of the lung
Filosso P. L.;
2021
Abstract
Primary lung neuroendocrine tumors (NETs) represent a rare but diverse set of neoplasms occurring with increasing frequency. Well-differentiated NETs, also known as bronchial carcinoids, are classified as either typical carcinoids or intermediate-grade atypical carcinoids and are best treated with formal anatomic lung resection with systematic lymphadenectomy. Small-cell and large-cell neuroendocrine carcinomas represent more aggressive histologies though surgical resection with adjuvant chemotherapy remains the standard approach for well-selected patients with localized disease. This chapter reviews the diagnosis and surgical management of primary lung NETs.
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