Purpose: To describe a case of Acute Syphilitic Posterior Placoid Chorio-retinitis characterized by a peculiar optical coherence tomography (OCT) finding. Methods: The patient underwent comprehensive ophthalmic examination, including ultra-wide field fundus photography, fluorescein angiography, and spectral-domain OCT. Results: This finding was characterized by hyper-reflective lesions located between the retinal pigment epithelium and the outer plexiform layer involving almost the outer nuclear layer. Conclusion: We suggest that this finding could be a sign of outer retina inflammation related to the Syphilis infection and may be helpful in the early diagnosis of ASPCC.
A novel finding in the diagnosis of acute syphilitic posterior placoid chorioretinitis: A case report / Rissotto, F.; Sacconi, R.; Oldoni, G.; Beretta, F.; Miserocchi, E.; Bandello, F.; Querques, G.. - In: EUROPEAN JOURNAL OF OPHTHALMOLOGY. - ISSN 1120-6721. - 35:6(2025), pp. 46-49. [10.1177/11206721251351066]
A novel finding in the diagnosis of acute syphilitic posterior placoid chorioretinitis: A case report
Querques G.
2025
Abstract
Purpose: To describe a case of Acute Syphilitic Posterior Placoid Chorio-retinitis characterized by a peculiar optical coherence tomography (OCT) finding. Methods: The patient underwent comprehensive ophthalmic examination, including ultra-wide field fundus photography, fluorescein angiography, and spectral-domain OCT. Results: This finding was characterized by hyper-reflective lesions located between the retinal pigment epithelium and the outer plexiform layer involving almost the outer nuclear layer. Conclusion: We suggest that this finding could be a sign of outer retina inflammation related to the Syphilis infection and may be helpful in the early diagnosis of ASPCC.
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