Innovative knee ligament recovery: ultrasound-guided peptide injections for grade II medial collateral ligament tears

This case report presents an innovative, minimally invasive treatment for a Grade II medial collateral ligament (MCL) tear, utilizing ultrasound-guided injections of low molecular weight peptides (LWPs) and hydrolyzed collagen with vitamin C supplementation. The approach adds to the surgical literature by demonstrating the feasibility of a minimally invasive, image-guided therapy aimed at enhancing ligament healing, an important consideration for individuals seeking faster recovery and return to physical activities. A 50-year-old male amateur athlete presented with acute medial knee pain following a soccer game, diagnosed as a Grade II MCL tear. Key concerns included pain management and rapid recovery to resume sports activities. The patient was treated with two rounds of ultrasound-guided injections directly into the MCL, containing a novel solution of LWPs, hydrolyzed collagen, and vitamin C. This treatment was complemented by a physiotherapy regimen. Clinical outcomes showed significant improvements in pain, knee functionality, and stability, allowing a return to sports within three months. The patient achieved significant improvement as assessed by patient-reported outcome measures (PROMs), including a reduction in Visual Analogue Scale (VAS) pain scores from 7 to 1 and an increase in the Lysholm Knee Scoring Scale from 25 to 85. The case highlights the potential benefits of using targeted, biologically active compounds in non-surgical treatment of ligament injuries. It underscores the importance of innovative treatments that can significantly reduce recovery time and improve functional outcomes for athletes, suggesting a promising area for further research and application in sports medicine and orthopedics.