The measurements of serum gonadotropins, testosterone, SHBG, and calculated free testosterone have a central role in the endocrine diagnostics of male hypogonadism and infertility. Additional hormone determinations include the newest specific markers of Sertoli (inhibin B, anti-mullerian hormone) and Leydig (insulin-like factor 3) cell function. Dynamic tests (GnRH and hCG stimulation tests) are useful in the assessment of pituitary and testis reserve capacity. In selected cases, molecular biology techniques may be helpful in the endocrine workup.
Endocrine Laboratory Diagnosis / Simoni, M.; Nieschlag, E.. - (2023), pp. 133-141. [10.1007/978-3-031-31574-9_7]
Endocrine Laboratory Diagnosis
Simoni M.;
2023
Abstract
The measurements of serum gonadotropins, testosterone, SHBG, and calculated free testosterone have a central role in the endocrine diagnostics of male hypogonadism and infertility. Additional hormone determinations include the newest specific markers of Sertoli (inhibin B, anti-mullerian hormone) and Leydig (insulin-like factor 3) cell function. Dynamic tests (GnRH and hCG stimulation tests) are useful in the assessment of pituitary and testis reserve capacity. In selected cases, molecular biology techniques may be helpful in the endocrine workup.
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