Myoclonus has multiple clinical manifestations and heterogeneous generators and etiologies, encompassing a spectrum of disorders and even physiological events. This paper, developed from a teaching course conducted by the Neurophysiology Commission of the Italian League against Epilepsy, aims to delineate the main types of myoclonus, identify potential underlying neurological disorders, outline diagnostic procedures, elucidate pathophysiological mechanisms, and discuss appropriate treatments. Neurophysiological techniques play a crucial role in accurately classifying myoclonic phenomena, by means of simple methods such as EEG plus polymyography (EEG + Polymyography), evoked potentials, examination of long-loop reflexes, and often more complex protocols to study intra-cortical inhibition-facilitation. In clinical practice, EEG + Polymyography often represents the first step to identify myoclonus, acquire signals for off-line studies and plan the diagnostic work-up.
A Reappraisal on cortical myoclonus and brief Remarks on myoclonus of different Origins / Canafoglia, L.; Meletti, S.; Bisulli, F.; Alvisi, L.; Assenza, G.; D'Orsi, G.; Dubbioso, R.; Ferlazzo, E.; Ferri, L.; Franceschetti, S.; Gambardella, A.; Granvillano, A.; Licchetta, L.; Nucera, B.; Panzica, F.; Perulli, M.; Provini, F.; Rubboli, G.; Strigaro, G.; Suppa, A.; Tartara, E.; Cantalupo, G.. - In: CLINICAL NEUROPHYSIOLOGY PRACTICE. - ISSN 2467-981X. - 9:(2024), pp. 266-278. [10.1016/j.cnp.2024.10.001]
A Reappraisal on cortical myoclonus and brief Remarks on myoclonus of different Origins
Meletti S.;
2024
Abstract
Myoclonus has multiple clinical manifestations and heterogeneous generators and etiologies, encompassing a spectrum of disorders and even physiological events. This paper, developed from a teaching course conducted by the Neurophysiology Commission of the Italian League against Epilepsy, aims to delineate the main types of myoclonus, identify potential underlying neurological disorders, outline diagnostic procedures, elucidate pathophysiological mechanisms, and discuss appropriate treatments. Neurophysiological techniques play a crucial role in accurately classifying myoclonic phenomena, by means of simple methods such as EEG plus polymyography (EEG + Polymyography), evoked potentials, examination of long-loop reflexes, and often more complex protocols to study intra-cortical inhibition-facilitation. In clinical practice, EEG + Polymyography often represents the first step to identify myoclonus, acquire signals for off-line studies and plan the diagnostic work-up.File | Dimensione | Formato | |
---|---|---|---|
1-s2.0-S2467981X2400026X-main.pdf
Open access
Tipologia:
Versione pubblicata dall'editore
Dimensione
3.35 MB
Formato
Adobe PDF
|
3.35 MB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris