Aim:Evaluating the incidence and course of COVID-19 in cancer patients treated with immunotherapy.Patients & methods:We reported the influenza-like illness events with diagnosis of COVID-19 within the patient cohort enrolled in the prospective observational multicenter INVIDIa-2 study in the single center of Parma.Results:Among 53 patients, eight experienced influenza-like illness during the influenza season 2019/2020, and three of them had diagnosis of COVID-19. They were males, elderly, with cardiovascular disease. Radiological features of COVID-19 pneumonitis were found in all of three cases, although the pharyngeal swab resulted positive in only two. Two of these three patients died due to respiratory failure.Conclusion:Cancer patients are at high risk of severe events from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Clinical Impact of COVID-19 in a Single-Center Cohort of a Prospective Study in Cancer Patients Receiving Immunotherapy / Bersanelli, Melissa; Zielli, Teresa; Perrone, Fabiana; Casartelli, Chiara; Pratticò, Fabiana; Rapacchi, Elena; Camisa, Roberta; Tognetto, Michele; Clemente, Alberto; Giannarelli, Diana; Rebuzzi, Sara Elena; Leonetti, Alessandro; Bordi, Paola; Tiseo, Marcello; Buti, Sebastiano. - In: IMMUNOTHERAPY. - ISSN 1750-743X. - 12:15(2020), pp. 1139-1148. [10.2217/imt-2020-0211]
Clinical Impact of COVID-19 in a Single-Center Cohort of a Prospective Study in Cancer Patients Receiving Immunotherapy
Bersanelli, Melissa;Casartelli, Chiara;Leonetti, Alessandro;
2020
Abstract
Aim:Evaluating the incidence and course of COVID-19 in cancer patients treated with immunotherapy.Patients & methods:We reported the influenza-like illness events with diagnosis of COVID-19 within the patient cohort enrolled in the prospective observational multicenter INVIDIa-2 study in the single center of Parma.Results:Among 53 patients, eight experienced influenza-like illness during the influenza season 2019/2020, and three of them had diagnosis of COVID-19. They were males, elderly, with cardiovascular disease. Radiological features of COVID-19 pneumonitis were found in all of three cases, although the pharyngeal swab resulted positive in only two. Two of these three patients died due to respiratory failure.Conclusion:Cancer patients are at high risk of severe events from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
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