Kasugai et al. show that associative learning, such as fear conditioning, elicits concerted structural and functional plasticity of amygdala GABAergic synapses. This process regulates both somatic and dendritic inhibition and may tune amygdala circuit responses to threats.
Structural and Functional Remodeling of Amygdala GABAergic Synapses in Associative Fear Learning / Kasugai, Y.; Vogel, E.; Hortnagl, H.; Schonherr, S.; Paradiso, E.; Hauschild, M.; Gobel, G.; Milenkovic, I.; Peterschmitt, Y.; Tasan, R.; Sperk, G.; Shigemoto, R.; Sieghart, W.; Singewald, N.; Luthi, A.; Ferraguti, F.. - In: NEURON. - ISSN 0896-6273. - 104:4(2019), pp. 781-794.e4. [10.1016/j.neuron.2019.08.013]
Structural and Functional Remodeling of Amygdala GABAergic Synapses in Associative Fear Learning
Ferraguti F.
2019
Abstract
Kasugai et al. show that associative learning, such as fear conditioning, elicits concerted structural and functional plasticity of amygdala GABAergic synapses. This process regulates both somatic and dendritic inhibition and may tune amygdala circuit responses to threats.
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