IntroductionIt has recently been reported that it is possible to monitor lung oxygenation (rSO2L) by near-infrared spectroscopy (NIRS) in preterm infants with respiratory distress syndrome (RDS). Thus, our aim was to assess the possibility of monitoring rSO2L in infants with evolving and established bronchopulmonary dysplasia (BPD) and to evaluate if rSO2L correlates with BPD severity and other oxygenation indices.MethodsWe studied 40 preterm infants with gestational age <= 30 weeks at risk for BPD. Patients were continuously studied for 2 h by NIRS at 28 +/- 7 days of life and 36 weeks +/- 7 days of postmenstrual age.ResultsrSO2L was similar at the first and second NIRS recordings (71.8 +/- 7.2 vs. 71.4 +/- 4.2%) in the overall population, but it was higher in infants with mild than in those with moderate-to-severe BPD at both the first (73.3 +/- 3.1 vs. 71.2 +/- 3.2%, p = .042) and second (72.3 +/- 2.8 vs. 70.5 +/- 2.8, p = .049) NIRS recording. A rSO2L cutoff value of 71.6% in the first recording was associated with a risk for moderate-to-severe BPD with a sensitivity of 66% and a specificity of 60%. Linear regression analysis demonstrated a significant positive relationship between rSO2L and SpO2/FiO2 ratio (p = .013) and a/APO2 (p = .004).ConclusionsMonitoring of rSO2L by NIRS in preterm infants with evolving and established BPD is feasible and safe. rSO2L was found to be higher in infants with mild BPD, and predicts the risk for developing moderate-to-severe BPD and correlates with other indices of oxygenation.

Measurement of lung oxygenation by near‐infrared spectroscopy in preterm infants with bronchopulmonary dysplasia / Dani, Carlo; Miselli, Francesca; Zini, Tommaso; Scarponi, Davide; Luzzati, Michele; Sarcina, Davide; Fusco, Monica; Dianori, Francesco; Berardi, Alberto. - In: PEDIATRIC PULMONOLOGY. - ISSN 8755-6863. - 59:6(2024), pp. 1631-1637. [10.1002/ppul.26955]

Measurement of lung oxygenation by near‐infrared spectroscopy in preterm infants with bronchopulmonary dysplasia

Miselli, Francesca;Zini, Tommaso;Scarponi, Davide;Berardi, Alberto
2024

Abstract

IntroductionIt has recently been reported that it is possible to monitor lung oxygenation (rSO2L) by near-infrared spectroscopy (NIRS) in preterm infants with respiratory distress syndrome (RDS). Thus, our aim was to assess the possibility of monitoring rSO2L in infants with evolving and established bronchopulmonary dysplasia (BPD) and to evaluate if rSO2L correlates with BPD severity and other oxygenation indices.MethodsWe studied 40 preterm infants with gestational age <= 30 weeks at risk for BPD. Patients were continuously studied for 2 h by NIRS at 28 +/- 7 days of life and 36 weeks +/- 7 days of postmenstrual age.ResultsrSO2L was similar at the first and second NIRS recordings (71.8 +/- 7.2 vs. 71.4 +/- 4.2%) in the overall population, but it was higher in infants with mild than in those with moderate-to-severe BPD at both the first (73.3 +/- 3.1 vs. 71.2 +/- 3.2%, p = .042) and second (72.3 +/- 2.8 vs. 70.5 +/- 2.8, p = .049) NIRS recording. A rSO2L cutoff value of 71.6% in the first recording was associated with a risk for moderate-to-severe BPD with a sensitivity of 66% and a specificity of 60%. Linear regression analysis demonstrated a significant positive relationship between rSO2L and SpO2/FiO2 ratio (p = .013) and a/APO2 (p = .004).ConclusionsMonitoring of rSO2L by NIRS in preterm infants with evolving and established BPD is feasible and safe. rSO2L was found to be higher in infants with mild BPD, and predicts the risk for developing moderate-to-severe BPD and correlates with other indices of oxygenation.
2024
59
6
1631
1637
Measurement of lung oxygenation by near‐infrared spectroscopy in preterm infants with bronchopulmonary dysplasia / Dani, Carlo; Miselli, Francesca; Zini, Tommaso; Scarponi, Davide; Luzzati, Michele; Sarcina, Davide; Fusco, Monica; Dianori, Francesco; Berardi, Alberto. - In: PEDIATRIC PULMONOLOGY. - ISSN 8755-6863. - 59:6(2024), pp. 1631-1637. [10.1002/ppul.26955]
Dani, Carlo; Miselli, Francesca; Zini, Tommaso; Scarponi, Davide; Luzzati, Michele; Sarcina, Davide; Fusco, Monica; Dianori, Francesco; Berardi, Alberto
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1340177
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