BackgroundThe detection of cutaneous metastases (CMs) from various primary tumours represents a diagnostic challenge.ObjectivesOur aim was to evaluate the general characteristics and dermatoscopic features of CMs from different primary tumours.MethodsRetrospective, multicentre, descriptive, cross-sectional study of biopsy-proven CMs.ResultsWe included 583 patients (247 females, median age: 64 years, 25%-75% percentiles: 54-74 years) with 632 CMs, of which 52.2% (n = 330) were local, and 26.7% (n = 169) were distant. The most common primary tumours were melanomas (n = 474) and breast cancer (n = 59). Most non-melanoma CMs were non-pigmented (n = 151, 95.6%). Of 169 distant metastases, 54 (32.0%) appeared on the head and neck region. On dermatoscopy, pigmented melanoma metastases were frequently structureless blue (63.6%, n = 201), while amelanotic metastases were typified by linear serpentine vessels and a white structureless pattern. No significant difference was found between amelanotic melanoma metastases and CMs of other primary tumours.ConclusionsThe head and neck area is a common site for distant CMs. Our study confirms that most pigmented melanoma metastasis are structureless blue on dermatoscopy and may mimic blue nevi. Amelanotic metastases are typified by linear serpentine vessels and a white structureless pattern, regardless of the primary tumour.

Dermatoscopic patterns of cutaneous metastases: A multicentre cross-sectional study of the International Dermoscopy Society / Tiodorovic, Danica; Stojkovic-Filipovic, Jelena; Marghoob, Ashfaq; Argenziano, Giuseppe; Puig, Susana; Malvehy, Josep; Tognetti, Linda; Pietro, Rubegni; Akay, Bengu Nisa; Zalaudek, Iris; Haenssle, Holger A; Müller-Christmann, Christine; Cinotti, Elisa; Perrot, Jean Luc; Zaballos, Pedro; Bakos, Renato Marchiori; Thomas, Luc; Peris, Ketty; Lallas, Aimilios; Apalla, Zoe; Kreusch, Juergen F; Tromme, Isabelle; Stratigos, Alexandros J; Pizzichetta, Maria Antonietta; Kandolf, Lidija; Longo, Caterina; Blum, Andreas; Tanaka, Masaru; Hofmann-Wellenhof, Rainer; Jovic, Andrija; Paoli, John; Buljan, Marija; Espasandín-Arias, Martina; Cabo, Horacio; Saa, Sonia Rodrigiez; Salerni, Gabriel; Nazzaro, Gianluca; Kaminska-Winciorek, Grazyna; Damiani, Giovanni; Geszti, Franciska; Kittler, Harald. - In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - ISSN 1468-3083. - (2024), pp. N/A-N/A. [10.1111/jdv.19962]

Dermatoscopic patterns of cutaneous metastases: A multicentre cross-sectional study of the International Dermoscopy Society

Longo, Caterina;Damiani, Giovanni;
2024

Abstract

BackgroundThe detection of cutaneous metastases (CMs) from various primary tumours represents a diagnostic challenge.ObjectivesOur aim was to evaluate the general characteristics and dermatoscopic features of CMs from different primary tumours.MethodsRetrospective, multicentre, descriptive, cross-sectional study of biopsy-proven CMs.ResultsWe included 583 patients (247 females, median age: 64 years, 25%-75% percentiles: 54-74 years) with 632 CMs, of which 52.2% (n = 330) were local, and 26.7% (n = 169) were distant. The most common primary tumours were melanomas (n = 474) and breast cancer (n = 59). Most non-melanoma CMs were non-pigmented (n = 151, 95.6%). Of 169 distant metastases, 54 (32.0%) appeared on the head and neck region. On dermatoscopy, pigmented melanoma metastases were frequently structureless blue (63.6%, n = 201), while amelanotic metastases were typified by linear serpentine vessels and a white structureless pattern. No significant difference was found between amelanotic melanoma metastases and CMs of other primary tumours.ConclusionsThe head and neck area is a common site for distant CMs. Our study confirms that most pigmented melanoma metastasis are structureless blue on dermatoscopy and may mimic blue nevi. Amelanotic metastases are typified by linear serpentine vessels and a white structureless pattern, regardless of the primary tumour.
2024
N/A
N/A
Dermatoscopic patterns of cutaneous metastases: A multicentre cross-sectional study of the International Dermoscopy Society / Tiodorovic, Danica; Stojkovic-Filipovic, Jelena; Marghoob, Ashfaq; Argenziano, Giuseppe; Puig, Susana; Malvehy, Josep; Tognetti, Linda; Pietro, Rubegni; Akay, Bengu Nisa; Zalaudek, Iris; Haenssle, Holger A; Müller-Christmann, Christine; Cinotti, Elisa; Perrot, Jean Luc; Zaballos, Pedro; Bakos, Renato Marchiori; Thomas, Luc; Peris, Ketty; Lallas, Aimilios; Apalla, Zoe; Kreusch, Juergen F; Tromme, Isabelle; Stratigos, Alexandros J; Pizzichetta, Maria Antonietta; Kandolf, Lidija; Longo, Caterina; Blum, Andreas; Tanaka, Masaru; Hofmann-Wellenhof, Rainer; Jovic, Andrija; Paoli, John; Buljan, Marija; Espasandín-Arias, Martina; Cabo, Horacio; Saa, Sonia Rodrigiez; Salerni, Gabriel; Nazzaro, Gianluca; Kaminska-Winciorek, Grazyna; Damiani, Giovanni; Geszti, Franciska; Kittler, Harald. - In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - ISSN 1468-3083. - (2024), pp. N/A-N/A. [10.1111/jdv.19962]
Tiodorovic, Danica; Stojkovic-Filipovic, Jelena; Marghoob, Ashfaq; Argenziano, Giuseppe; Puig, Susana; Malvehy, Josep; Tognetti, Linda; Pietro, Rubegni; Akay, Bengu Nisa; Zalaudek, Iris; Haenssle, Holger A; Müller-Christmann, Christine; Cinotti, Elisa; Perrot, Jean Luc; Zaballos, Pedro; Bakos, Renato Marchiori; Thomas, Luc; Peris, Ketty; Lallas, Aimilios; Apalla, Zoe; Kreusch, Juergen F; Tromme, Isabelle; Stratigos, Alexandros J; Pizzichetta, Maria Antonietta; Kandolf, Lidija; Longo, Caterina; Blum, Andreas; Tanaka, Masaru; Hofmann-Wellenhof, Rainer; Jovic, Andrija; Paoli, John; Buljan, Marija; Espasandín-Arias, Martina; Cabo, Horacio; Saa, Sonia Rodrigiez; Salerni, Gabriel; Nazzaro, Gianluca; Kaminska-Winciorek, Grazyna; Damiani, Giovanni; Geszti, Franciska; Kittler, Harald
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1339428
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