Lourenço et al. demonstrate that burst firing of layer 5 pyramidal neurons (PNs) induces long-term potentiation of inhibition (LTPi). LTPi strongly affects PN input/output spikes, prevents transfer of information across cortical layers, and affects phase locking of PN firing to cognition-relevant rhythmic activity.
Modulation of coordinated activity across cortical layers by plasticity of inhibitory synapses / Lourenco, J.; De Stasi, A. M.; Deleuze, C.; Bigot, M.; Pazienti, A.; Aguirre, A.; Giugliano, M.; Ostojic, S.; Bacci, A.. - In: CELL REPORTS. - ISSN 2211-1247. - 30:3(2020), pp. 630-641.e5. [10.1016/j.celrep.2019.12.052]
Modulation of coordinated activity across cortical layers by plasticity of inhibitory synapses
Giugliano M.;
2020
Abstract
Lourenço et al. demonstrate that burst firing of layer 5 pyramidal neurons (PNs) induces long-term potentiation of inhibition (LTPi). LTPi strongly affects PN input/output spikes, prevents transfer of information across cortical layers, and affects phase locking of PN firing to cognition-relevant rhythmic activity.
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