The results of this pilot study provide the first evidence that the hERG1 protein is expressed in primary BC, and its expression associates with molecular subtype. hERG1 apparently behaves as a protective factor, since it contributes to identify a subset of patients with better outcome. Overall, these data suggest that hERG1 might be an additional tool for the management of BC, nevertheless further investigations are warranted to better clarify hERG1 role and clinical usefulness in BC.
hERG1 channel expression associates with molecular subtypes and prognosis in breast cancer / Iorio, Jessica; Meattini, Icro; Bianchi, Simonetta; Bernini, Marco; Virginia, Maragna; Luca, Dominici; Casella, Donato; Vezzosi, Vania; Orzalesi, Lorenzo; Nori, Jacopo; Livi, Lorenzo; Arcangeli, Annarosa; Lastraioli, Elena. - In: CANCER CELL INTERNATIONAL. - ISSN 1475-2867. - 18:1(2018), pp. 93-100. [10.1186/s12935-018-0592-1]
hERG1 channel expression associates with molecular subtypes and prognosis in breast cancer
Marco Bernini;
2018
Abstract
The results of this pilot study provide the first evidence that the hERG1 protein is expressed in primary BC, and its expression associates with molecular subtype. hERG1 apparently behaves as a protective factor, since it contributes to identify a subset of patients with better outcome. Overall, these data suggest that hERG1 might be an additional tool for the management of BC, nevertheless further investigations are warranted to better clarify hERG1 role and clinical usefulness in BC.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Iorio 2018.pdf
Open access
Tipologia:
Versione pubblicata dall'editore
Dimensione
4.28 MB
Formato
Adobe PDF
|
4.28 MB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
