Although imatinib may be effective in hypereosinophilic syndromes, the exact response kinetics are not known. Imatinib was administered at 100-400 mg/d each week in a 12-week response-oriented schedule, targeting a complete clinical and haematological remission (CR). CR was achieved in 11/23 patients (6/6 with
A short low-dose imatinib trial allows rapid identification of responsive patients in hypereosinophilic syndromes / Intermesoli, T; Delaini, F; Acerboni, S; Salmoiraghi, S; Spinelli, O; Guerini, V; Vannucchi, Am; Mappa, S; Rossi, G; Rossi, V; Di Bona, E; Paratore, S; Carobbio, A; Rambaldi, A; Barbui, T; Bassan, R. - In: BRITISH JOURNAL OF HAEMATOLOGY. - ISSN 1365-2141. - 147:5(2009), pp. 681-685. [10.1111/j.1365-2141.2009.07893.x]
A short low-dose imatinib trial allows rapid identification of responsive patients in hypereosinophilic syndromes
Carobbio A;
2009
Abstract
Although imatinib may be effective in hypereosinophilic syndromes, the exact response kinetics are not known. Imatinib was administered at 100-400 mg/d each week in a 12-week response-oriented schedule, targeting a complete clinical and haematological remission (CR). CR was achieved in 11/23 patients (6/6 with
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