To the Editor: Andrade et al. (Jan. 12 issue)(1) found that an initial strategy of catheter cryoballoon ablation in patients with paroxysmal atrial fibrillation was associated with a lower incidence of persistent atrial fibrillation, and a lower burden of arrhythmia than therapy with antiarrhythmic drugs during 3 years of follow-up. The article extends the initial findings of the Early Aggressive Invasive Intervention for Atrial Fibrillation (EARLY-AF) trial.(2) Given the number of participants (303 patients) and the relatively short follow-up, it would have been difficult to detect mortality benefits of cryoballoon ablation. Both the EARLY-AF and the STOP AF First(3) trials . . .
Progression of Atrial Fibrillation after Cryoablation / Boriani, G.; Imberti, J. F.; Vitolo, M.. - In: THE NEW ENGLAND JOURNAL OF MEDICINE. - ISSN 1533-4406. - 388:14(2023), pp. 1339-1341. [10.1056/NEJMc2301604]
Progression of Atrial Fibrillation after Cryoablation
Boriani G.;Imberti J. F.;Vitolo M.
2023
Abstract
To the Editor: Andrade et al. (Jan. 12 issue)(1) found that an initial strategy of catheter cryoballoon ablation in patients with paroxysmal atrial fibrillation was associated with a lower incidence of persistent atrial fibrillation, and a lower burden of arrhythmia than therapy with antiarrhythmic drugs during 3 years of follow-up. The article extends the initial findings of the Early Aggressive Invasive Intervention for Atrial Fibrillation (EARLY-AF) trial.(2) Given the number of participants (303 patients) and the relatively short follow-up, it would have been difficult to detect mortality benefits of cryoballoon ablation. Both the EARLY-AF and the STOP AF First(3) trials . . .
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