Patients with a history of primary brain tumors can be eligible for organ donation under extended criteria. The risk assessment of tumor transmission via organ transplant in primary brain tumors is primarily based on the assessment of tumor histotype and grade. Previous surgeries, chemo-/radiotherapy, and ventriculo-peritoneal shunt placement can lead to a disruption of the blood-brain barrier, concurring to an increase in the transmission risk.
Risk factors of extraneural spreading in astrocytomas and oligodendrogliomas in donors with gliomas: A systematic review / Ammendola, Serena; Barresi, Valeria; Bariani, Elena; Girolami, Ilaria; D'Errico, Antonia; Brunelli, Matteo; Cardillo, Massimo; Lombardini, Letizia; Carraro, Amedeo; Boggi, Ugo; Cain, Owen; Neil, Desley; Eccher, Albino. - In: WORLD JOURNAL OF TRANSPLANTATION. - ISSN 2220-3230. - 12:6(2022), pp. 131-141. [10.5500/wjt.v12.i6.131]
Risk factors of extraneural spreading in astrocytomas and oligodendrogliomas in donors with gliomas: A systematic review
Eccher, Albino
2022
Abstract
Patients with a history of primary brain tumors can be eligible for organ donation under extended criteria. The risk assessment of tumor transmission via organ transplant in primary brain tumors is primarily based on the assessment of tumor histotype and grade. Previous surgeries, chemo-/radiotherapy, and ventriculo-peritoneal shunt placement can lead to a disruption of the blood-brain barrier, concurring to an increase in the transmission risk.
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