Different strategies have been proposed to target neoangiogenesis in gliomas, besides those targeting Vascular Endothelial Growth Factor (VEGF). The chemokine Interleukin-8 (IL-8) has been shown to possess both tumorigenic and proangiogenic properties. Although different pathways of induction of IL-8 gene expression have been already elucidated, few data are available on its post-transcriptional regulation in gliomas.
Regulation of IL-8 gene expression in gliomas by microRNA miR-93 / Fabbri, E., Brognara, E., Montagner, G., Ghimenton, C., Eccher, A., Cantù, C., Khalil, S., Bezzerri, V., Provezza, L., Bianchi, N., Finotti, A., Borgatti, M., Moretto, G., Chilosi, M., Cabrini, G., Gambari, R.. - In: BMC CANCER. - ISSN 1471-2407. - 15:1(2015), pp. 661-661. [10.1186/s12885-015-1659-1]
Regulation of IL-8 gene expression in gliomas by microRNA miR-93
ECCHER, Albino;
2015
Abstract
Different strategies have been proposed to target neoangiogenesis in gliomas, besides those targeting Vascular Endothelial Growth Factor (VEGF). The chemokine Interleukin-8 (IL-8) has been shown to possess both tumorigenic and proangiogenic properties. Although different pathways of induction of IL-8 gene expression have been already elucidated, few data are available on its post-transcriptional regulation in gliomas.
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