Oil Red O is a useful tool to assess donor liver steatosis on frozen sections during transplantation. Steatosis is a frequent finding in liver evaluation during transplantation, accounting for 9% to 26% of biopsied donor liver. The degree of macrovesicular steatosis is classified as mild, moderate, and severe; the latter is considered an absolute contraindication to liver transplantation because it is associated with poor allograft outcome. Because of the scarcity of organs, there is a debate whether livers with less severe macrovesicular steatosis are still suitable for transplant. Consequently, tools or methods that allow a more accurate intraoperative assessment of steatosis on frozen sections are mandatory. The aim of this study is to improve intraoperative evaluation of steatosis during transplantation using Oil Red O stain on liver biopsies.
Oil Red O Is a Useful Tool to Assess Donor Liver Steatosis on Frozen Sections During Transplantation / Riva, G., Villanova, M., Cima, L., Ghimenton, C., Bronzoni, C., Colombari, R., Crestani, M., Sina, S., Brunelli, M., D'Errico, A., Montin, U., Novelli, L., Eccher, A.. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 50:10(2018), pp. 3539-3543. [10.1016/j.transproceed.2018.06.013]
Oil Red O Is a Useful Tool to Assess Donor Liver Steatosis on Frozen Sections During Transplantation
Eccher, A
2018
Abstract
Oil Red O is a useful tool to assess donor liver steatosis on frozen sections during transplantation. Steatosis is a frequent finding in liver evaluation during transplantation, accounting for 9% to 26% of biopsied donor liver. The degree of macrovesicular steatosis is classified as mild, moderate, and severe; the latter is considered an absolute contraindication to liver transplantation because it is associated with poor allograft outcome. Because of the scarcity of organs, there is a debate whether livers with less severe macrovesicular steatosis are still suitable for transplant. Consequently, tools or methods that allow a more accurate intraoperative assessment of steatosis on frozen sections are mandatory. The aim of this study is to improve intraoperative evaluation of steatosis during transplantation using Oil Red O stain on liver biopsies.
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